Biophysical Society 66th Annual Meeting Program Guide

1920-Pos Board B378 RBM20 ASOS IMPROVE VENTRICULAR FILLING IN A MOUSE MODEL WITH INCREASED TITIN-BASED STIFFNESS. Victor Badillo Lisakowski , Mi - chael H. Radke, Thiago Britto-Borges, Dieter Kubli, René Jüttner, Pragati Parakkat, Jacobo López Carballo, Judith Hüttemeister, Martin Liss, Arne Hansen, Christoph Dieterich, AdamMullick, Michael Gotthardt 1921-Pos Board B379 HARNESSING MULTISCALE MODELS OF A DILATED CARDIOMYOPATHY MUTATION FOR PRECISION MEDICINE. Lina Greenberg, William Stump, Andrea L. Bredemeyer, Kory J. Lavine, Michael J. Greenberg 1922-Pos Board B380 RIBONUCLEOTIDE REDUCTASE MEDIATED REGULATION OF MITOCHON - DRIAL ACTIVITY IN THE ADULT HEART. Majid Shakeri , Djelli Berisha, Amy Martinson, Jennifer Davis, Farid Moussavi-Harami 1923-Pos Board B381 ANTI-S2 PEPTIDES TARGET CARDIAC MYOSIN FOR IN VIVO RESPONS - ES. Douglas D. Root , Dua'a Quedan, Motamed Qadan, Bryana M. Levitan, Mindy S. Thompson, Kenneth S. Campbell 1924-Pos Board B382 STRAIN-RATE OF STRETCH AFFECTS CROSSBRIDGE DETACHMENT KINET - ICS DURING RELAXATION IN TWITCHING, INTACT CARDIAC TRABECU - LAE. Charles S. Chung , Bertrand C.W. Tanner 1925-Pos Board B383 HYPERTROPHIC AND DILATED CARDIOMYOPATHY-ASSOCIATED TNNT- 2 PATHOGENIC VARIANTS INDUCE NUCLEUS REMODELING IN HIPSC-CM MODELS. Isabella Leite Coscarella , Lili Wang, Jerome Irianto, Bjorn C. Knollmann, Prescott B. Chase, J. Renato Pinto 1926-Pos Board B384 INCREASED LENGTH-DEPENDENT ACTIVATION OF HUMAN ENGINEERED HEART TISSUE AFTER CHRONIC TREATMENT WITH ALPHA-1A-ADRENER - GIC AGONIST. Cassady Rupert, Elizabeth Cortez-Toledo, Javier E. Lopez, Naomi C. Chesler, Paul C. Simpson, Stuart G. Campbell, Anthony J. Baker 1927-Pos Board B385 Travel Award Winner ROLE OF CARDIAC ALPHA-ACTININ 2 PATHOGENIC VARIANT IN HUMAN MYOCARDIUMMECHANICS. Michelle C. Rodriguez Garcia , Maicon Landim-Vieira, Jeffrey Schmeckpeper, Lili Wang, Moore B. Shoemaker, Prescott B. Chase, Bjorn C. Knollmann, J. Renato Pinto 1928-Pos Board B386 REVERSAL OF MITOCHONDRIAL DYSFUNCTION AND RIGHT VENTRICU - LAR FAILURE AFTER CHRONIC TREATMENT WITH ALPHA-1A-ADRENERGIC AGONIST. On Yeung Li , Guanying Wang, Philip M. Swigart, Bahador Marz - ban, Paul C. Simpson, Naomi C. Chesler, Daniel A. Beard, Anthony J. Baker 1929-Pos Board B387 CORRELATIONS BETWEEN CELLULAR-LEVEL CONTRACTILE PROPERTIES AND ECHOCARDIOGRAPHIC-BASED MEASUREMENTS OF CARDIAC FUNC - TION IN ORGAN DONORS AND PATIENTS WITH HEART FAILURE. Gregory N. Milburn , Katherine L. Thompson, Emma J. Birks, Kenneth S. Campbell 1930-Pos Board B388 A COMPUTATIONAL MODEL OF RIGHT VENTRICULAR REMODELLING IN THE PRESENCE OF PULMONARY ARTERIAL HYPERTENSION. Oscar Odeigah , Joakim Sundnes, Michael Bennington, Daniela Valdez-Jasso

1908-Pos Board B366 THE STRUCTURAL BASIS OF SUBSTRATE PROMISCUITY WITHIN THE SMALL MULTIDRUG RESISTANCE FAMILY. Ali A. Kermani , Randy Stock - bridge 1909-Pos Board B367 CORRELATING THE TRANSPORT CYCLE OF SMALL MULTIDRUG RESIS - TANCE TRANSPORTERS. Daipayan Sarkar , Jessica L. Egelston, Josh V. Vermaas 1910-Pos Board B368 STUDIES OF TRANSPORT PROPERTIES OF EMRE PROTEIN - SIMULATION BY MOLECULAR DYNAMICS. Jakub Jurasz , Milosz Wieczor, Jacek Czub, Maciej Baginski 1911-Pos Board B369 BIOCHEMICAL AND STRUCTURAL INSIGHT OF REGULATION IN YEAST VACUOLAR ABC TRANSPORTER YCF1. Nitesh K. Khandelwal , Cinthia R. Millan, Samantha I. Zangari, Samantha Avila, Dewight Williams, Tarjani M. Thaker, Thomas M. Tomasiak 1912-Pos Board B370 COPPER-DEPENDENT ATP7B N-TERMINAL DOMAIN DYNAMICS IN TWO REACTION-CYCLE INTERMEDIATES. Fredrik Orädd , Magnus Andersson Cardiac Muscle Mechanics and Structure II (Boards B371 - B388) 1913-Pos Board B371 PSEUDO-ACETYLATION OF ACTIN K326 AND K328 INCREASES DURA - TION AND FORCE OF CONTRACTION IN MOUSE CARDIOMYOCYTES. Axel Fenwick , Vivek P. Jani, Aditi Madan, Anthony Cammarato 1914-Pos Board B372 Travel Award Winner CARDIAC FIBROSIS RHEOLOGY ELUCIDATED BY AFMWHOLE-SPHEROID STRESS-RELAXATION. Michele Zanetti , Laura Andolfi, Marco Lazzarino 1915-Pos Board B373 GLYCOGEN SYNTHASE KINASE 3Β LOCALIZES TO THE Z-DISC TO MAINTAIN LENGTH DEPENDENT ACTIVATION. Marisa J. Stachowski , Maria Papa - daki, Thomas Martin, Weikang Ma, Henry M. Gong, Stephanie Shao, Shi Shen, Nitha Aima Muntu, Jody L. Martin, Christine S. Moravec, Stuart G. Campbell, Thomas C. Irving, Jonathan A. Kirk 1916-Pos Board B374 DNA TENSION PROBES SHOW THAT CARDIOMYOCYTE MATURATION IS SENSITIVE TO THE PN TRACTION FORCES TRANSMITTED BY INTEG - RINS. Sk Aysha Rashid , Aaron T. Blanchard, Joseph D. Combs, Natasha Fernandez, Hee Cheol Cho, Khalid Salaita 1917-Pos Board B375 Travel Award Winner MECHANISMS OF DYSFUNCTION IN PATIENT-DERIVED CARDIOMYOCYTES WITH THE HYPERTROPHIC CARDIOMYOPATHY-MYOSIN BINDING PRO - TEIN-C E258K MUTATION. Sonette Steczina , J. Manuel Pioner, Marianna Langione, Neil Wood, Giulia Vitale, Chiara Tesi, Raffaele Coppini, Cecilia Ferrantini, Michael J. Previs, Corrado Poggesi, Michael Regnier 1918-Pos Board B376 Travel Award Winner MAPPING THE BINDING INTERACTION OF MYBP-C AND MYOSIN IN HYPERTROPHIC CARDIOMYOPATHY. Fiona L. Wong , Thomas A. Bunch, Allison L. Steedman, Victoria C. Lepak, Brett A. Colson 1919-Pos Board B377 ENGINEERED HEART TISSUES FOR STUDYING TWITCH TENSION AND INOTROPIC PHARMACOLOGICAL INTERVENTIONS. Marianna Langione , J. Manuel Pioner, Sonette Steczina, Giulia Vitale, Elisabetta Cerbai, Chiara Tesi, Raffaele Coppini, Michael Regnier, Corrado Poggesi, Cecilia Fer - rantini

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