Biophysical Society 66th Annual Meeting Program Guide

Protein Structure and Conformation IV (Boards B1 - B25) 2171-Pos Board B1 A DIFFERENT MECHANISM OF C-TYPE INACTIVATION IN THE KV-LIKE KCSA MUTANT E71V. Ahmed Rohaim , Bram Vermeulen, Jing Li, Felix Kümmerer, Federico Napoli, Lydia Blachowicz, Markus Weingarth, Benoit Roux 2172-Pos Board B2 INTRAMEMBRANE SERINE PROTEASE CATALYSIS IN DIFFERENT PHYSICAL ENVIRONMENTS. Mojgan Asadi 2173-Pos Board B3 ANCESTOR OF ALL EXTRINSIC APOPTOTIC CASPASES. David A. Diaz 2174-Pos Board B4 ANALYSIS OF THE INTERACTION OF PLEXIN-A FAMILY WITH COLLAPSIN RESPONSE MEDIATOR PROTEIN-2. Giacomo M. Di Mauro , Maria Iannucci, Christina Whitehouse, Juliette Smyers, Matthias Buck 2175-Pos Board B5 ARGININE ANCHOR POINTS IN HISTONE H3 TAIL DYNAMICS. Casey Zoss, Emeleeta A. Paintsil, Erin F. Hammonds, Emma A. Morrison 2176-Pos Board B6 MOLECULAR BASIS OF INFLAMMASOME ADAPTOR INHIBITION BY THE ASC-C ISOFORM. Anthony Waterston 2177-Pos Board B7 A UHM-ULM INTERFACE CONTRIBUTES TO THE PRE-MRNA SPLICING FUNCTIONS OF U2AF2 AND SF3B1. Justin W. Galardi , Victoria N. Bela, Nazish N. Jeffery, Eliezra Glasser, Sarah Loerch, Jermaine L. Jenkins, Mary J. Pulvino, Clara L. Kielkopf 2178-Pos Board B8 DOMAIN DYNAMICS AND PLASTICITY OF THE TRANSPOSON-ENCODED CASCADE-TNIQ SYSTEM. Amun C. Patel , Pablo R. Arantes, Giulia Palermo 2179-Pos Board B9 SYNERGETIC COMBINATION OF PHOTOLUMINESCENCE SPECTROSCOPY WITH MICROSECOND X-RAY FOOTPRINTING. Sayan Gupta , Brandon Russell, Line Kristensen, Behzad Rad, Corie Ralston 2180-Pos Board B10 EVOLUTIONARY ORIGINS OF REDOX SENSITIVITY IN GLUCOKINASES. Johanna E. Papa , A. C. Whittington, Brian G. Miller 2181-Pos Board B11 STRUCTURAL BASIS OF SIGNAL TRANSDUCTION WITHIN ENVIRONMENTAL SENSING PAS REGULATED SER/THR KINASES. Roksana Azad 2182-Pos Board B12 CRYO-EM STRUCTURAL DETERMINATION OF MET18, A SCAFFOLD PROTEIN FOR IRON-SULFUR PROTEIN MATURATION. Sheena Vasquez 2183-Pos Board B13 THE VITAMIN B3 TRANSPORTER PNUC: SUBSTRATE INDUCED CONFORMA - TION CHANGE AND TRIMERIZATION COOPERATIVITY MECHANISM. Tongyi Dou , Jiansen Jiang 2184-Pos Board B14 COMPLEX FORMATION OF RUBISCO AND RUBISCO ACTIVASE. Kazi Waheeda , Po-Lin Chiu 2185-Pos Board B15 Travel Award Winner STRUCTURAL CHARACTERIZATION OF TYROSINE KINASE SUBSTRATE BINDING AND ARRAY-BASED FUNCTIONAL PEPTIDE SCREENING OF SRC KINASE. Dan Xie , Yixing Sun, Casey J. Krusemark, Andy Hudmon, Carol B. Post

2186-Pos Board B16 DISTINCT MECHANISM OF INTERACTIONS BETWEEN NCS1 AND TB 3+ / EU 3+ . Md. Shofiul Alam , Jaroslava Miksovska 2187-Pos Board B17 NEAR NATIVE STATES THAT BYPASS BIOLOGICAL QUALITY CONTROLS AND ITS CONSEQUENCES AND PREVALENCE ACROSS THE PROTEOME. Ian M. Sitarik 2188-Pos Board B18 EXPLOITING CONFORMATIONAL TRANSITIONS IN PROTEIN KINASES FOR THE DISCOVERY OF POLYVALENT INHIBITORS. Gabriel da Silva , Brenda M. Rubenstein 2189-Pos Board B19 TUNICATE CIONA INTESTINALIS STRUCTURE ANALYSIS. Mina Mozafari , Megan A. Rocha, Natalia Kozlyuk, Rachel W. Martin 2190-Pos Board B20 PROTOMER POLYMORPHISM IN MECHANICALLY STRETCHED VON WIL - LEBRAND FACTOR. Maria Csilla Csanyi , Tímea Feller, Tamas Bozo, Miklós S. Kellermayer, Jolan Harsfalvi 2191-Pos Board B21 CHARACTERIZATION OF FISH LENS CRYSTALLINS: MODELS OF PROTEIN ADAPTATION FOR SOLUBILITY AND COLD TOLERANCE. Andrew D. Durham , Megan A. Rocha, Brenna Norton-Baker, Rachel W. Martin 2192-Pos Board B22 INVESTIGATING THE DYNAMIC PROPERTIES OF THE TRANSMEMBRANE DOMAINS OF PINHOLIN S 21 68 USING MECHANICAL ALIGNMENT EPR SPEC - TROSCOPY. Rasal H. Khan 2193-Pos Board B23 Travel Award Winner INSIGHTS INTO THE STRUCTURAL DYNAMICS AND RNA BINDING OF THE DENGUE NONSTRUCTURAL 5 (NS5) PROTEIN. Juliet O. Obi , James K. Fields, Daniel J. Deredge 2194-Pos Board B24 FIP200, A MOLECULAR BRIDGE TO AUTOPHAGY INITIATION. Adam Yokom , James H. Hurley, Chunmei Chang, Xiaoshan Shi 2195-Pos Board B25 THE CONFORMATIONAL CHANGES CAUSED BY MUTATIONS IN ALPHA- GALACTOSIDASE A LEADING TO FABRY DISEASE. Camila Molina , Efecan Aral, Scott C. Garman Protein Dynamics and Allostery II (Boards B26 - B53) 2196-Pos Board B26 Travel Award Winner CHARACTERIZING PH SENSITIVE MOLECULAR MECHANISM OF NETWORKS OF IONIZABLE RESIDUES. Papa Kobina Van Dyck , Katharine A. White 2197-Pos Board B27 A NOVEL MECHANISM FOR ACTIVATED PROCESS IN BIOMOLECULES. Shanshan Wu 2198-Pos Board B28 IN SILICO STUDY ON THE SELECTIVE INHIBITION OF ALZHEIMER’S DISEASE (AD) PATHOLOGICAL COMPLEX CDK5-P25 BY PEPTIDE P5 IN PRESENCE OF MUNC 18 (P67). Tejaswi Tammareddy , Antonio Cardone, Sergio A. Hassan, Harish C. Pant, Mary Brady, Walid Keyrouz, Ram Sriram, Jeffery B. Klauda 2199-Pos Board B29 COMPUTATIONAL STUDIES OF THE DYNAMICS OF SARS-COV-2 SPIKE, MEMBRANE, AND NUCLEOCAPSID PROTEINS. Mandira Dutta , Gregory A. Voth

W E

D N

E S

D A Y

135