Biophysical Society 66th Annual Meeting Program Guide

2441-Pos Board B271 DEHYDROPIANDROSTERONE (DHEA) REDUCES CORE BODY TEM - PERATURE AND PROTECTS AGAINST HEAT STRESS INTOLERANCE IN RYR1-T4826I MALIGNANT HYPERTHERMIA SUSCEPTIBLE MICE. Shane Antrobus, Wei Feng , Isaac N. Pessah 2442-Pos Board B272 BENZYDAMINE INHIBITS NEURONAL EXCITABILITY INDUCED BY INFLAM - MATORY MEDIATORS TO RELIEF PAIN. Antonio V. Ferrer-Montiel , Mag - dalena Nikolaeva-Koleva, Mateo Vergassola, Giorgina Mangano, Lorenzo Polenzani, Ana Espinosa, Lorella Ragni, Isabel Devesa 2443-Pos Board B273 FINE-TUNING THE IMMUNOLOGICAL SIGNATURE OF MAST CELLS USING TRPC PHOTOPHARMACOLOGY. Denis Krivic , Bernadett Bacsa, Annarita Graziani, Klaus Groschner 2444-Pos Board B274 MECHANICAL AND PHARMACOLOGICAL ACTIVATION OF PIEZO1 CHAN - NELS CHARACTERIZED BY HIGH THROUGHPUT ELECTROPHYSIOLO - GY. Andrea Bruggemann , Nicoletta Murciano, Maria Giustina Rotordam, Markus Rapedius, Nadine Becker, Melanie J. Ludlow, Gregory Parson - age, Kevin Cuthbertson, Richard Foster, David J. Beech 2445-Pos Board B275 ION PATHWAYS IN THE HUMAN PANNEXIN 1 CHANNEL. Ian J. Orozco , Zheng Ruan, Juan Du, Wei Lu 2446-Pos Board B276 ION CHANNELS AND MYOGENESIS IN DUCHENNE MUSCULAR DYSTRO - PHY: A FIRST CHARACTERIZATION IN DIFFERENTIATING WILD-TYPE AND DYSTROPHIC MYOCYTES. Alessandro Giovanni Cerchiara , Paola Imbrici, Dominic Wells, Ornella Cappellari, Annamaria De Luca 2447-Pos Board B277 NEGATIVE ALLOSTERIC MODULATION OF GLUN3-CONTAINING NMDA RECEPTORS WITH A NOVEL MECHANISM OF ACTION. Nirvan Rouzbeh 2448-Pos Board B278 COMPUTER MODELLING THE ROOT CAUSE OF CYSTIC FIBROSIS. Miro A. Astore , Po-Chia Chen, Shafagh Waters, Serdar Kuyucak Anion Channels (Boards B279 - B285) 2449-Pos Board B279 STRUCTURAL BASIS FOR THE CHROMOGRANIN B ANION CHANNEL IN REGULATED SECRETION. Gaya P. Yadav , Qiu-Xing Jiang 2450-Pos Board B280 VOLTAGE DEPENDENT ANION CHANNELS AND ADENINE NUCLEOTIDE TRANSLOCATORS: A DYSFUNCTIONAL ASSOCIATION IN STEM CELLS? Kareem A. Heslop , Amandine Rovini, Eduardo N. Maldonado 2451-Pos Board B281 STRUCTURAL INSIGHT OF THE PROTON-ACTIVATED CHLORIDE (PAC) CHANNEL REVEALED BY CRYO-EM. Zheng Ruan , James Osei-Owusu, Juan Du, Zhaozhu Qiu, Wei Lü 2452-Pos Board B282 Travel Award Winner MODULATION OF PROTON-ACTIVATED CHLORIDE (PAC) CHANNEL BY PIP2. Ljubica Mihaljevic , Zheng Ruan, James Osei-Owusu, Wei Lu, Zhaozhu Qiu 2453-Pos Board B283 INVESTIGATING THE CROSSTALK BETWEEN CLC-1 C-TERMINAL CBS DOMAINS AND THE TM REGION. Héctor Gaitán-Peñas, Rubén Martínez- Buey, Raul Estevez

2454-Pos Board B284 INVESTIGATING INTERACTING PARTNERS OF BESTROPHIN CHAN - NELS. Alec Kittredge , Aaron P. Owji, Yu Zhang, Tingting Yang 2455-Pos Board B285 ACTIVATION OF TMEM16F LIPID SCRAMBLASE: TRANSPORT OF IONS AND LIPIDS. Jian Huang , Jianhan Chen, ZhiGuang Jia Mitochondria in Cell Life and Death (Boards B286 - B311) 2456-Pos Board B286 DEPLETION OF MITOCHONDRIAL INORGANIC POLYPHOSPHATE (POLYP) IN MAMMALIAN CELLS CAUSES METABOLIC SHIFT FROM OXIDATIVE PHOSPHORYLATION TO GLYCOLYSIS. Maria E. Solesio Torregrosa , Lihan Xe, Brendan McIntyre, Mathew Ellenberger, Erna Mitaishvili, Siddharth Bhadra-Lobo, Lisa F Bettcher, Jason N. Bazil, Daniel Raftery, Ursula Jakob, Evgeny Pavlov 2457-Pos Board B287 REDUCTION IN ACTIVITY AND ABUNDANCE OF MITOCHONDRIAL SUPERCOMPLEXES IN RIGHT VENTRICLE OF A PULMONARY HYPERTEN - SION RATS. Wenzhuo Ma , Alexander Vang, Scarlett Huck, Clarissa C. Muller, Thomas Mancini, Preston Nicely, Peng Zhang, Gaurav Choud - hary, Richard T. Clements 2458-Pos Board B288 MITOCHONDRIAL ROS SIGNALING DURING SYNAPTIC POTENTIA - TION. Irina Stavrovskaya, Erna Mitaishvilli, Bethany Kristi Morin, Aria Walls, Grace Terry, Pablo M. Peixoto 2459-Pos Board B289 LOW INTENSITY MAGNETIC FIELDS STIMULATE THE ELECTRON TRANS - PORT CHAIN IN HEART MITOCHONDRIA. Shey-Shing Sheu , Gisela Beutner, Huoy-Jen Yuh, Ilan Goldenberg, Arthur Moss 2460-Pos Board B290 IN SEARCH FOR PEPTIDE THERAPEUTICS TO REDUCE Α-SYNUCLEIN- INDUCED MITOCHONDRIAL DYSFUNCTION IN PARKINSON’S DIS - EASE. Megha Rajendran 2461-Pos Board B291 CARDIOMYOCYTE-SPECIFIC AMPK DOUBLE-KO IMPAIRS MITOCHONDRI - AL FUNCTION AND PERFORMANCE AT HIGH WORKLOAD. Malgorzata Tokarska-Schlattner , Laurence Kay, Pascale Perret, Raffaella Isola, Stéphane Attia, Frédéric Lamarche, Cindy Tellier, Cécile Cottet-Rousselle, Amjad Uneisi, Marc Foretz, Hervé Dubouchaud, Cathérine Ghezzi, Chris - tian Zuppinger, Benoit Viollet, Uwe Schlattner 2462-Pos Board B292 MITOCHONDRIAL CRISTAE ULTRASTRUCTURE ADAPTATIONS IN THE SE - NESCENT HEART. Gonzalo Barrientos, Isidora E. Molina, Wileidy Gómez, Francisco Díaz-Castro, Andrea delCampo-Sefir, Luís Garrido, Silke Morris, Katherina Psathaki, Hugo Verdejo, Karin B. Busch, Verónica Eisner 2463-Pos Board B293 CHARACTERIZING SUBSTRATE DEPENDENT DIFFERENTIAL REGULATION OF MITOCHONDRIAL BIOENERGETICS IN THE HEART AND KIDNEY COR - TEX AND OUTER MEDULLA USING COMPUTATIONAL MODELING. Xiao Zhang, Nomrata Tomar, shima sadri, Said H. Audi, Allen W. Cowley Jr., Ranjan K. Dash 2464-Pos Board B294 MITOCHONDRIAL MICRODOMAIN DISRUPTION RESULTS IN SINUS NODE DYSFUNCTION IN HEART FAILURE. Lu Ren, Raghavender R. Gopireddy, Guy Perkins, Valeriy Timofeyev, Yankun Lyu, James Overton, Wilson Xu, Nathan Grainger, Luis F. Santana, Xiao-Dong Zhang, Ebenezer N. Yamoah, Elena N. Dedkova, Manuel F. Navedo, Nipavan Chiamvimon - vat, Phung N. Thai

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