Biophysical Society 66th Annual Meeting Program Guide

Platform Bioengineering and Biosensors 8:15 am - 10:15 am, South, Level Two, Room 215/216 Co-Chairs Weiqiang Chen, New York University, USA Maria Rosa Antognazza, Italian Institute of Technology, Italy 74 -Plat 8:30 am ACTINOSOMES: CONDENSATE-TEMPLATED PROTEINACEOUS CONTAIN- ERS FOR ENGINEERING SYNTHETIC CELLS. Ketan A. Ganar , Liza Leijten, Siddharth Deshpande 75 -Plat 8:45 am Travel Award Winner CELL-PERMEABLE FLUORESCENT CHEMICAL SENSORS FOR IMAGING PHOSPHOINOSITIDES. Rajasree Kundu , Samsuzzoha Mondal, amitava Chandra, Ravindra Venkatramani, Ankona Datta 76 -Plat 9:00 am SURFACE DECORATION OF BIOMIMETIC WNT5A LIGANDS PROMOTES CYTOTOXIC T-CELL MECHANOTRANSDUCTION AND ACTIVATION. Rui Li , Walida Ali, Ngoc Luu, Apratim Bajpai, Weiqiang Chen 77 -Plat 9:15 am CONJUGATED POLYMERS OPTICALLY REGULATE THE FATE OF ENDOTHE - LIAL PROGENITOR CELLS. Maria Rosa Antognazza 78 -Plat 9:30 am TOPOLOGIES OF SYNTHETIC GENE CIRCUIT FOR OPTIMAL FOLD CHANGE ACTIVATION IN BACTERIAL BIOSENSORS. Ramez Daniel 79 -Plat 9:45 am MESH ELECTRODE ARRAYS FOR INTEGRATION WITH ELECTROGENIC OR - GANOIDS. Csaba Forro , Thomas Li, Xiao Yang, Ching-Ting Tsai, Bianxiao Cui, Sergiu Pasca 80 -Plat 10:00 am MEASURING THE DYNAMICS OF GLUCOSE-STIMULATED OXYGEN CON- SUMPTION IN INDIVIDUAL PANCREATIC ISLETS USING ISLET-ON-A-CHIP. Romario Regeenes, Yufeng Wang, Anthony Piro, Michael B. Wheeler, Jonathan V. Rocheleau CID Committee Meeting 8:30 am - 10:30 am, South, Level Three, Room 312 Career Development Center Workshop Networking for Biophysicists: How to Create Your Unicorn Career 9:00 am - 10:00 am, Esplanade, Room 151 In this session, we will discuss how to leverage networking to create a unique, customized career, which we call Your Unicorn Career. We will address how to understand your unique value, skills and interests and how to align that with employers who will hire you. We will discuss vari - ous methods for finding and building win-win collaborations with people in different professions and pathways to create opportunities for your unicorn career to come to fruition.

62 -Plat 9:30 am POSSIBLE MECHANISMS UNDERLYING THE DYNAMIC ASSEMBLY OF CALCIUM ENTRY UNITS: THE ROLE OF TEMPERATURE AND PH. Barbara Girolami, Matteo Serano, Laura Pietrangelo, Feliciano Protasi 63 -Plat 9:45 am A NOVEL 3D SPATIAL MODEL OF MOUSE SINOATRIAL NODE CELLS FOR INVESTIGATING IMPACT OF MICROSTRUCTURE CHANGES ON PACE- MAKER ACTIVITY. Haibo Ni , Di Lang, Stefano Morotti, Alexey V. Glukhov, Eleonora Grandi 64 -Plat 10:00 am HIGH-RESOLUTION CRYO-EM STRUCTURES OF THE MAGNESIUM-INHIBIT- ED AND CALCIUM-INACTIVATED RYR1. Ashok R. Nayak, Warin Rangubpit, Alex H. Will, Yifan Hu, Kavita Iyer, Pablo Castro-Hartmann, Joshua J. Lobo, Kelly A. Dryden, Takashi Murayama, Pornthep Sompornpisut, Montserrat Samso Platform Ligand-Gated Channels I 8:15 am - 10:15 am, South, Level Two, Room 212/213/214 Co-Chairs Raghavendar Reddy Sanganna Gari, Weill Cornell Medicine, USA Eric N. Senning, University of Texas at Austin, USA 65 -Plat 8:15 am DIRECT VISUALIZATION OF TRPV2 INTRINSIC DISORDERED REGIONS AND INTERACTIONS WITH CANNABINOIDS. Raghavendar Reddy Sanganna Gari , Ruth Pumroy, Vera Moiseenkova-Bell, Grigory Tagiltsev, Simon Scheuring 66 -Plat 8:30 am THE MOLECULAR NATURE OF TEMPERATURE DEPENDENCE OF THE TR pm 2 CHANNEL. Adam Bartok , Laszlo Csanady 67 -Plat 8:45 am PHOSPHOINOSITIDE REGULATION OF TR pm 3 CHANNELS. Siyuan Zhao , Vincenzo Carnevale , Vincenzo Carnevale , Tibor Rohacs 68 -Plat 9:00 am STRUCTURES OF THE TR pm 5 CHANNEL ELUCIDATE MECHANISMS OF AC- TIVATION AND INHIBITION. Emery D. Haley , Zheng Ruan, Ian J. Orozco, Becca Roth, Mark Sabat, Richard Myers, Juan Du, Wei Lu 69 -Plat 9:15 am A POTENTIAL SONOGENETIC ACTUATOR FOR ULTRASOUND-MEDIATED NEUROMODULATION. Lu Zhao 70 -Plat 9:30 am Travel Award Winner PHOTOCROSSLINKING OF ASICS REVEALS THE ACIDIC POCKET TO BE AN ALLOSTERIC HUB. Matthew L. Rook , Tyler A. Couch, David M. MacLean 71 -Plat 9:45 am CONFORMATIONAL DYNAMICS OF THE PROKARYOTIC CNG CHANNEL STHK. Pierce Eggan , William N. Zagotta 72 -Plat 10:00 am GENOMIC VARIANCE ANALYSIS TO CONSTRAIN MUTAGENESIS STUDIES OF TRPV1 SUBUNIT INTERFACES. Eric N. Senning , Taylor Mott, Jordan Ibarra, Nivitha Kalendula

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