Biophysical Society 66th Annual Meeting Program Guide

Symposium Membrane Morphology/Membrane and Cytoskeletal Phenomena - Relation to Membrane Function 10:45 am - 12:45 pm, South, Level Three, Room 301/302 Chair Min Wu, Yale University, USA 81-Symp 10:45 am CONTROL OF MEMBRANE FUSION PORE DIAMETER CONSTRICTION AND WIDENING. Robert Zorec 82-Symp 11:15 am MORPHOLOGY AND MECHANICS OF MEMBRANE NANOTUBES INTER - ACTING WITH RECONSTITUTED ACTIN NETWORKS. Clément Campillo 83-Symp 11:45 am THE MEMBRANE PHASE TRANSITION COUPLES TO PROTEIN SCAFFOLDS TO PRODUCE FUNCTIONAL ORGANIZATION AT THE CELL SURFACE. Sarah A. Shelby, Mason Rouches, Benjamin B. Machta, Sarah Veatch 84-Symp 12:15 pm COOPERATIVITY AND COMPETITION IN CORTICAL ACTIN WAVE FORMA - TION. Chee San Tong, Maohan Su, Xiangle Jerry Chua, Min Wu Symposium New and Notable 10:45 am - 12:45 pm, South, Level Three, Room 303/304 Co-chairs Elizabeth Komives, University of California, San Diego, USA Arthur G. Palmer, III, Columbia University, USA No Abstract 10:45 am STRUCTURE AND FUNCTION OF THE HUMAN SODIUM LEAK CHANNELO - SOME. Stephan Pless No Abstract 11:15 am PRION PROTEIN BIOPHYSICS THROUGH THE LENS OF LIQUID-LIQUID PHASE SEPARATION: A TALE OF AN INTRINSICALLY DISORDERED TAIL. Samrat Mukhopadhyay No Abstract 11:45 am REVEALING ATOMIC-SCALE MOLECULAR DIFFUSION OF A TRANSCRIP - TION FACTOR DOMAIN PROTEIN ALONG DNA. Jin Yu No Abstract 12:15 pm THE NON-CANONICAL RECEPTOR CRYO-EM STRUCTURE OF GPCR-RGS REVEALS UNUSUAL BIOLOGY OF ORPHAN RECEPTORS AND THE FORMA - TION OF SIGNALING GPCR-RGS NANOCOMPLEXES. Tina Izard Platform Protein Structure and Conformation I 10:45 am - 12:45 pm, South, Level Two, Room 201/202/203 Co-Chairs Emma Carroll, University of California, Berkeley, USA Blake Hill, Medical College of Wisconsin, USA 85-Plat 10:45 am FAST, SIMPLE MOLECULAR ENTROPY CALCULATIONS FROM VORONOI DI - AGRAMS OF A SINGLE STRUCTURE. Pranav M. Khade , Robert L. Jernigan 86 -Plat 11:00 am PROTEIN ADAPTATION IN EXTREMOPHILES: A STORY OF SEQUENCE, STRUCTURE AND OSMOLYTES. Mayank M. Boob , Yousef Sakhnini, Brahmmi Patel, Taras V. Pogorelov, Martin Gruebele

87 -Plat 11:15 am EVOLUTIONARY ORIGINS OF A HETEROMERIC PROTEIN-PROTEIN IN - TERACTION THAT REGULATES MAMMALIAN GLUCOSE HOMEOSTASIS. Joshua I. Santiago , A. C. Whittington, Brian G. Miller 88 -Plat 11:30 am MOLECULAR RECOGNITION OF PATHOLOGICAL TAU FIBRIL CONFORMA - TIONS. Emma Carroll , Kelly Montgomery, Taia Wu, Jason E. Gestwicki 11:45 am Flash Talks 89-Plat 12:00 pm PRESTIN'S STRUCTURAL CYCLE AND THE MOLECULAR BASIS OF ELECTRO - MOTILITY IN OUTER HAIR CELLS. Navid Bavi , Michael D. Clark, Gustavo F. Contreras, Rong Shen, Bharat Reddy, Wieslawa Milewski, Eduardo Perozo 90-Plat 12:15 pm ENGRAILED HOMEODOMAIN USES AN ELECTROSTATIC SPRING-LOADED MECHANISM TO CHANGE CONFORMATION UPON BINDING TO DNA. Benjamin Tanielian , Nicola D'Amelio, Mourad Sadqi, Victor Munoz 91-Plat 12:30 pm STRUCTURAL STUDIES OF HUMAN FIS1 REVEAL A DYNAMIC REGION IMPORTANT FOR DRP1 RECRUITMENT AND MITOCHONDRIAL FISSION. Kelsey A. Meacham , John M. Egner, Megan C. Harwig, Maxx H. Tessmer, Elizabeth L. Noey, Ugochukwu K. Ihenacho, Francis C. Peterson, Michael E. Widlansky, Blake R. Hill Platform Optical Microscopy and Superresolution Imaging I 10:45 am - 12:45 pm, South, Level Two, Room 204/205/206 Co-Chairs Bei Liu, University of North Carolina at Chapel Hill, USA Lisa-Maria Needham, University of Wisconsin-Madison, USA 92-Plat 10:45 am Travel Award Winner CHROMATIN-SPECIFIC LABEL-FREE DYNAMIC IMAGING BY HIGH-SPEED SCATTERING-BASED INTERFERENCE OPTICAL MICROSCOPY. Chia-Ni Tsai , Yi-Teng Hsiao, Te-Hsin Chen, Chia-Lung Hsieh 93-Plat 11:00 am THX-A NEXT GENERATION PROBE FOR THE EARLY DETECTION OF amY - LOID AGGREGATES. Lisa-Maria Needham , Judith Weber, Juan A. Varela, James W.B. Fyfe, Dung T. Do, Catherine K Xu, David Klenerman, Christo - pher M. Dobson, Christopher A. Hunter, Sarah E. Bohndiek, Thomas N. Snaddon, Steven F. Lee 94-Plat 11:15 am SEEING INSIDE THE CELL USING LIVE-PAINT: A NEWWAY TO IMAGE PROTEINS IN LIVING CELLS USING SUPERRESOLUTION MICROSCOPY. Zoe Gidden , Curran Oi, Mathew Horrocks, Lynne Regan 95-Plat 11:30 am Travel Award Winner GENOME OLIGOPAINT VIA LOCAL DENATURATION FLUORESCENCE IN SITU HYBRIDIZATION (GOLD FISH) AND SINGLE-NUCLEOTIDE VARIATION DETECTION. Yanbo Wang , Wayne T. Cottle, Haobo Wang, Xinyu A. Feng, John Mallon, Momcilo Gavrilov, Roger Zou, Scott Bailey, Taekjip Ha 11:45 am Flash Talks 96-Plat 12:00 pm NOBIAS: ANALYZING ANOMALOUS DIFFUSION IN SINGLE-MOLECULE TRACKS WITH NONPARAMETRIC BAYESIAN INFERENCE. Ziyuan Chen , Laurent Geffroy, Julie Biteen 97-Plat 12:15 pm A NEW BIOSENSOR DESIGN REVEALS CONFORMATIONAL CHANGES OF SINGLE MOLECULES IN LIVING CELLS. Bei Liu , Nicholas K. Pinkin, Fred - erico M. Pimenta, Klaus M. Hahn

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