Biophysical Society 66th Annual Meeting Program Guide

154-Plat 4:15 pm DEPENDENCE OF TRNA DYNAMICS ON SUBUNIT ROTATION IN THE RIBO - SOME. Sandra Byju , Paul C. Whitford 155-Plat 4:30 pm Travel Award Winner ENTROPIC TUNING REGULATES THE FUNCTION OF BIOMOLECULAR MACHINES. Korak Kumar Ray , Colin D. Kinz-Thompson, Jingyi Fei, Ruben L. Gonzalez 156-Plat 4:45 pm ELONGATION FACTOR G AND BACTERIAL RESISTANCE TO amINOGLYCO - SIDES. Sara Gabrielli , Helmut Grubmuller, Lars V. Bock 157-Plat 5:00 pm 40S SCANNING UNVEILED BY SMFRET. Jinfan Wang , Joseph D. Puglisi 158-Plat 5:15 pm ORGANIZATION OF TRANSLATING SECRETOME MRNAS ON ENDOPLAS - MIC RETICULUM. Heejun Choi , Ya-Cheng Liao, Young J. Yoon, Jonathan Grimm, Luke D. Lavis, Robert H. Singer, Jennifer Lippincott-Schwartz 159-Plat 5:30 pm Travel Award Winner UNCOVERING THE UNIQUE BIOPHYSICAL PROPERTIES OF RNA POLYMER - ASES I, II, AND III. Ruth Q. Jacobs , Zachariah M. Ingram, Aaron L. Lucius, David A. Schneider 160-Plat 5:45 pm PROTEINS MEDIATING DIFFERENT DNA TOPOLOGIES BLOCK RNAP ELON - GATION WITH DIFFERENT EFFICIENCY. Yue Lu , Gustavo Borjas, Zsuzsanna Vörös, Ian Dodd, Keith Shearwin, David Dunlap, Laura Finzi Platform Membrane Dynamics 4:00 pm - 6:00 pm, South, Level Two, Room 209/210/211 Co-Chairs Michael F. Brown, University of Arizona, USA Lara G. Dresser, University of York, United Kingdom 161-Plat 4:00 pm CHOLESTEROL STIFFENING OF MODEL MAMMALIAN AND MICROBIAL MEMBRANES. Fathima T. Doole, Teshani Kumarage, Sudipta Gupta, Joshua A. Misa , Andrey V. Struts, Rana Ashkar, Michael F. Brown 162-Plat 4:15 pm LONG-TERM SUPERRESOLUTION IMAGING AND QUANTIFICATION OF LIVE-CELL PLASMA MEMBRANE BIOPHYSICAL PROPERTIES WITH SMART EXCHANGEABLE DYES. Pablo Carravilla , Anindita Dasgupta, Gaukhar Zhurgenbayeva, Dmytro I. Danylchuk, Andrey S. Klymchenko, Erdinc Sezgin, Christian Eggeling 163-Plat 4:30 pm ANALYSIS OF DISTINCT MULTI-LIPID CONFIGURATIONS REVEALS A MECH - ANISM FOR BILAYER SOFTENING. Henry J. Lessen , Andrew H. Beaven, Kayla Sapp, Alexander J. Sodt 164-Plat 4:45 pm ULTRASENSITIVE DETECTION OF CONFORMATIONAL CHANGES IN SINGLE LIPID VESICLES. Lara G. Dresser , Sarah Graham, Donato Conteduca, Char - ley Schaefer, Joanne Marrison, Peter J. O'Toole, Mark C. Leake, Steven Quinn 165-Plat 5:00 pm A NEW DOOR TO MEMBRANE MECHANICS: COLLECTIVE LIPID DYNAMICS INFORM BILAYER BENDING RIGIDITY. Milka Doktorova, George Khelash - vili, Rana Ashkar, Michael F. Brown 166-Plat 5:15 pm TAKING THE MONTE CARLO GAMBLE: HOW NOT TO BUCKLE UNDER THE PRESSURE! Yessica K. Gomez , AndrewM. Natale, James Lincoff, Charles W. Wolgemuth, Michael Grabe, John M. Rosenberg

167-Plat 5:30 pm THE EFFECT OF CROWDING ON THE DIFFUSIVITY OF PARTICLES ON A FREE-STANDING MEMBRANE. Paige Liu , Peter J. Beltramo 168-Plat 5:45 pm AN ATOMISTIC MODEL OF THE HUMAN STRATUM CORNEUM: PERME - ATION THROUGH THE LONG PERIODICITY PHASE. EFFECT OF A PRO- PENETRANT. Christian Jorgensen , Fabien Léonforte, Gustavo. S. Luengo, Sébastien Gregoire, Bruno Biatry, Peter D. Olmsted, Ann Detroyer Platform Muscle Structure and Function I 4:00 pm - 6:00 pm, South, Level Two, Room 212/213/214 Co-Chairs Vitold E. Galkin, Eastern Virginia Medical School, USA Luca Fusi, King's College London, United Kingdom 169-Plat 4:00 pm INTERACTION OF THE M-DOMAIN OF CARDIAC MYOSIN BINDING PROTEIN-C WITH THE NATIVE CARDIAC THIN FILAMENT. Cristina M. Risi , Betty Belknap, Samantha Harris, Howard D. White, Vitold E. Galkin 170-Plat 4:15 pm LOW TEMPERATURE AND OMECAMTIV MECARBIL AFFECT THE REGULA - TORY STATE OF THE THICK FILAMENT OF CARDIAC MYOCYTES IN DIAS - TOLE. Vincenzo Lombardi , Massimo Reconditi, Marco Caremani, Marco Linari, Matteo Marcello, Ilaria Morotti, Teyencheri Narayanan, Gabriella Piazzesi 171-Plat 4:30 pm COMPUTER SIMULATIONS DEMONSTRATE DUAL MECHANISMS THROUGH WHICH CARDIAC MYOSIN BINDING PROTEIN C REGULATES CONTRACTION. Sarah Kosta , Kerry S. McDonald, Julian Stelzer, Kenneth S. Campbell 172-Plat 4:45 pm STRUCTURAL DYNAMICS OF MYOSIN MOTORS AND TROPONIN IN DEMEMBRANATED CARDIAC TRABECULAE ACTIVATED BY PHOTOLYSIS OF CAGED CALCIUM. Elisabetta Brunello, Samina Juma, Alexander Alexan - drovich, Emma Smith, Malcolm Irving, Luca Fusi 173-Plat 5:00 pm STRUCUTRALLY DEFINING THE FLEXIBLE CARDIAC TROPONIN T LINKER. Andrea E. Deranek , Anthony Baldo, Melissa L. Lynn, Steven D. Schwartz, Jil C. Tardiff 174-Plat 5:15 pm Travel Award Winner MAPPING A TROPONIN I-LIKE INHIBITORY STRUCTURE IN THE C-TERMI - NAL REGION OF CARDIAC TROPONIN T. Tianxin Cao , Han-Zhong Feng, J.-P. Jin 175-Plat 5:30 pm N-TERMINAL DOMAINS OF CARDIAC TROPONIN-I MODULATE THIN FILA - MENT STRUCTURE. Elumalai Pavadai, Michael J. Rynkiewicz, Zeyu Yang, Ian Gould, Steven B. Marston, William Lehman 176-Plat 5:45 pm Travel Award Winner HUMAN CARDIAC TROPONIN T amINO TERMINUS IS REQUIRED FOR INHIBITION AND COOPERATIVE ACTIVATION OF CA 2+ -DEPENDENT THIN FILAMENT SLIDING. Yun Shi , Linda Stroud, Vincent A. LaBarbera, Quinton R. Sparrow, Fang Wang, Lauren E. Kessler, Brenda Schoffstall, Prescott B. Chase

F R I D A Y

S U N D A Y

24