Biophysical Society 66th Annual Meeting Program Guide

Excitation-Contraction Coupling (Boards B255 - B272)

417-Pos Board B241 REAL TIME IMAGING OF THE TRAFFICKING OF A HEDGEHOG PATHWAY KINESIN IN THE PRIMARY CILIUM. Pei-I Ku , Jamuna S. Sreeja, Benjamin R. Myers, Radhika Subramanian 418-Pos Board B242 EPR ON SITE-SELECTIVE SPIN-LABELED HUMAN CANNABINOID RECEP - TOR CB2. Alexei Yeliseev, Kaeli Zoretich, Levi Hooper, Walter E. Teague, Lioudmila Zoubak, Kirk G. Hines, Klaus Gawrisch 419-Pos Board B243 IMAGING GPCR SIGNALING BY POLARIZATION MICROSCOPY. Paul S. Miclea , Vendula Marková, Zuzana Vaitová, Alexey Bondar, Josef Lazar 420-Pos Board B244 SINGLE-MOLECULE ANALYSIS OF GPCR-MEDIATED B-ARRESTIN ACTIVA - TION. Daniel Terry 421-Pos Board B245 UNNATURAL AMINO ACID RECEPTOR INCORPORATION AS A PHOTOAF - FINITY TOOL FOR GPCR HETEROMER SIGNALING STUDIES. Brenda T. Winn , Diomedes E. Logothetis, Roman Manetsch, Meng Cui 422-Pos Board B246 AUTOREGULATION OF GPCR CONFORMATION AND SELECTIVE G PROTEIN ACTIVATION BY AN INTRINSICALLY DISORDERED LOOP REGION. Fredrik W. Sadler , Ning Ma, Nagarajan Vaidehi, Sivaraj Sivaramakrishnan 423-Pos Board B247 ROLE OF COMPLEXIN 2 IN THE REGULATION OF PANCREATIC ISLET CELL PHYSIOLOGY. Xue Wen Ng , Michael R. DiGruccio, David W. Piston 424-Pos Board B248 Travel Award Winner PYRUVATE KINASE AND GLP-1 RECEPTOR SIGNALING CONVERGE ON CAMP PRODUCTION TO ENHANCE INSULIN SECRETION. Sophie L. Lewandowski , Hannah R. Foster, Megan E. Capozzi, Jonathan E. Camp - bell, Matthew J. Merrins 425-Pos Board B249 Travel Award Winner ANAPLEROTIC AMINO ACIDS ATTENUATE GLUCAGON SECRETION BY LOWERING CAMP. Emily R. Knuth , Erli Jin, Hannah Foster, Matthew J. Board B250 EXPERIMENTAL STUDIES OF WILD TYPE A 2A RECEPTOR AND CHOLESTER - OL-BINDING RECEPTOR VARIANTS SUPPORT A MODEL FOR CHOLESTEROL AS AN ALLOSTERIC MODULATOR OF G PROTEIN COUPLING. Claire Mc - Graw, Kirsten S. Koretz, Edward R. Lyman, Anne S. Robinson 427-Pos Board B251 PROTON-GATED COINCIDENCE DETECTION IS A COMMON FEATURE OF GPCR SIGNALING. Daniel G. Isom 428-Pos Board B252 INSULIN-INDUCED RECOVERY IN KCNQ1/KCNE1-CURRENT ACCELERATES THE VENTRICULAR ACTION POTENTIAL REPOLARIZATION IN INSULIN- RESISTANT AGED-RATS VIA AFFECTING Β 3 -ADRENERGIC RECEPTORS. Yusuf Olgar, Aysegul Durak, Ceylan Verda Bitirim, Erkan Tuncay, Belma Turan 429-Pos Board B253 MECHANISM OF TRIPEPTIDE TRIMMING BY Γ-SECRETASE. Apurba Bhattarai , Sujan Devkota, Hung N. Do, Jinan Wang, Sanjay Bhattarai, Michael S. Wolfe, Yinglong Miao 430-Pos Board B254 Travel Award Winner HIDDEN INTERMEDIATE STATES OF NMDAR IN SYNAPSE DYNAMICS. Miaomiao He , Lonnie P. Wollmuth Merrins 426-Pos

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431-Pos Board B255 CALCIUM CURRENT MODULATION BY THE Γ1 SUBUNIT DEPENDS ON ALTERNATIVE SPLICING OF CA V 1.1. Yousra El Ghaleb , Nadine J. Ortner, Wilfried Posch, Monica L. Fernandez-Quintero, Wietske E. Tuinte, Stefania Monteleone, Henning J. Draheim, Klaus R. Liedl, Doris Wilflingseder, Jörg Striessnig, Petronel Tuluc, Bernhard E. Flucher, Marta Campiglio 432-Pos Board B256 SPECIFIC EFFECTS OF INDIVIDUAL C2 DOMAINS ON RECOVERY OF VOLTAGE-INDUCED SR CALCIUM RELEASE AFTER OSMOTIC SHOCK IN MUSCLE FIBERS FROM DYSFERLIN-NULL MICE. Valeriy I. Lukyanenko , Joaquin Muriel, Robert J. Bloch 433-Pos Board B257 HIGH-THROUGHPUT PLATFORM OF RECONSTITUTED SKELETAL MUSCLE DEPOLARIZATION-INDUCED CA 2+ RELEASE IN HEK293 CELLS. Takashi Murayama , Nagomi Kurebayashi, Takuya Kobayashi, Satoru Okazaki, Kyosuke Yamashiro, Takashi Sakurai 434-Pos Board B258 DEFINING THE ROLES OF VSD II & III OF CA V 1.1 IN REGULATING CALCIUM CURRENTS AND EC-COUPLING. Simone Pelizzari , Yousra El Ghaleb, Martin C. Heiss, Monica L. Fernández-Quintero, Petronel Tuluc, Marta Campiglio, Bernhard E. Flucher 435-Pos Board B259 DOES PROLONGED ACTION POTENTIAL ALWAYS INDICATE GREATER EARLY-AFTERDEPOLARIZATION RISK? Qingchu Jin , Joseph L. Greenstein, Raimond L. Winslow 436-Pos Board B260 ESTIMATING THE PROBABILITY OF EARLY AFTERDEPOLARIZATION AND PREDICTING ARRHYTHMIC RISK ASSOCIATED WITH LONG QT SYNDROME TYPE 1 MUTATIONS. Qingchu Jin, Joseph L. Greenstein, Raimond L. Board B261 PROTEIN KINASE D1 IS REQUIRED FOR FULL BETA-ADRENERGIC EF - FECTS ON CARDIAC CALCIUM HANDLING, BUT NOT UNDER CHRONIC STRESS. Juliana Mira Hernandez , Christopher Y. Ko, Erin Y. Shen, Avery Mandel, Emily R. Spencer, Nathan A.D. Kushner, Ashley R. Christensen, Donald M. Bers, Julie Bossuyt 438-Pos Board B262 SALTATORY CA 2+ -INDUCED-CA 2+ RELEASE PROPAGATION AMONG RYR2 CLUSTERS IN SINOATRIAL NODE CELLS ISOLATED FROM GFP-TARGETED RYR2 MICE. Syevda Tagirova , Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev 439-Pos Board B263 INITIATION AND MAINTENANCE OF ARRHYTHMOGENIC ACTION POTEN - TIAL WAVES NEAR THE INFARCT ZONE IN HEART FAILURE. Noah Wiesner , Bardia Ghayoumi, Haibo Ni, Bence Hegyi, Stefano Morotti, Donald M. Bers, Ye Chen-Izu, Eleonora Grandi, Daisuke Sato 440-Pos Board B264 COUPLING OF THE CONTRACTION AND INTRACELLULAR PH IN CARDIO - MYOCYTES. Yankun Lyu, Phung Thai, Lu Ren, Valeriy Timofeyev, Zhong Jian, Seojin Park, Kenneth S. Ginsburg, James Overton, Julie Bossuyt, Donald M. Bers, Ye Chen-Izu, Ebenezer N. Yamoah, Nipavan Chiamvimon - vat, Xiao-Dong Zhang Winslow 437-Pos

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