Biophysical Society 66th Annual Meeting Program Guide

612-Pos Travel Award Winner THE ROLE OF HIGHLY FUNCTIONAL Β-CELL SUBPOPULATIONS IN THE MULTICELLULAR ISLET. JaeAnn M. Dwulet , Jennifer K. Briggs, Richard K.P. Benninger 613-Pos Board B437 A DATA ASSIMILATION APPROACH TO PREDICT CELL POPULATION EPITHELIAL-MESENCHYMAL TRANSITION DYNAMICS. Mario J. Mendez , Matthew J. Hoffman, Elizabeth Cherry, Christopher A. Lemmon, Seth H. Weinberg 614-Pos Board B438 LEVY SKIMMER IN AN ASYMMETRIC RATCHET CHANNEL. Maryam Fathian 615-Pos Board B439 NECESSARY CONDITIONS FOR OSCILLATORY INSTABILITIES IN ACTIVE ME - CHANICAL NETWORKS. Neelima Sharma , Madhusudhan Venkadesan 616-Pos Board B440 ALGEBRA FOR LARGE MACROMOLECULAR COMPLEXES. Rebecca J. Rous - seau, Justin B. Kinney 617-Pos Board B441 NOISE DECOMPOSITION AND CONTROL IN SYNTHETIC GENE CIRCUITS COUPLED BY RESOURCE COMPETITION. Xiaojun Tian , Hanah Goetz, Austin Stone, Rong Zhang, Ying-Cheng Lai 618-Pos Board B442 TOPOLOGICAL DATA ANALYSIS OF HIGH DIMENSIONAL PROBABILITY LANDSCAPES OF BIOCHEMICAL REACTION NETWORKS USING PER - SISTENT HOMOLOGY. Farid Manuchehrfar , Wei Tian, Hubert Wagner, Herbert Edelsbrunner, Jie Liang 619-Pos Board B443 INTEGRATED MODELS, MODEL LANGUAGES, MODEL REPOSITORIES, SIMULATION EXPERIMENTS, SIMULATION TOOLS AND DATA VISUALIZA - TIONS ENABLES FACILE MODEL REUSE WITH BIOSIMULATIONS. Bilal Shaikh, Lucian P. Smith, Michael L. Blinov, Herbert M. Sauro, Ion I. Moraru , Jonathan R. Karr 620-Pos Board B444 THE PHENOMENON CANCER. Christina Pospisil Board B436 621-Pos Board B445 NATIONAL CENTER FOR IN-SITU TOMOGRAPHIC ULTRAMICROSCOPY AT NEW YORK STRUCTURAL BIOLOGY CENTER. Mykhailo Kopylov 622-Pos Board B446 GRAPHENE OXIDE SUPPORTED MICROWELL GRIDS FOR ICE-THICKNESS CONTROLLED CRYO-EM. Jungwon Park 623-Pos Board B447 CUSTOMMETALLIC ELECTRON MICROSCOPY GRIDS REDUCE SAMPLE HEATING IN SUPER-RESOLVED CRYOGENIC CORRELATIVE LIGHT AND ELECTRON MICROSCOPY EXPERIMENTS. Peter D. Dahlberg , Davis Perez, William E. Moerner 624-Pos Board B448 ROGFP2 AS AN ENVIRONMENTAL SENSOR FOR CRYOGENIC CORRELATIVE LIGHT AND ELECTRON MICROSCOPY. Davis Perez , Peter D. Dahlberg, An - nina M. Sartor, Jiarui Wang, Julia Borden, William E. Moerner 625-Pos Board B449 FREE-ENERGY PROFILES FROM SINGLE-MOLECULE CRYO-ELECTRON MICROSCOPY. Pilar Cossio Electron Microscopy (Boards B445 - B463)

598-Pos Board B422 ANALYSIS OF PARKIN PROTEIN USING CORRELATION MOLECULAR DY - NAMICS SIMULATIONS REVEALS PATHOGENIC AND HYPERACTIVE VARI - ANTS. Caleb A. Weber , Matt Coban, Thomas Caulfield 599-Pos Board B423 ION HOMEOSTASIS AND TENSION-SENSITIVE SURFACE AREA REGULA - TION: MODELING AUTONOMOUS CELLULAR PROCESSES FOR TRANS- MEMBRANE AND WITHIN-MEMBRANE HOMEOSTASIS. Bela Joos , Ziyi E. Liu, Aidan D. Bruce, Catherine E. Morris 600 -Pos Board B424 MORPHODYNAMICAL CELL-STATE DESCRIPTION VIA LIVE-CELL IMAGING TRAJECTORY EMBEDDING. Jeremy Copperman , Sean M. Gross, Young Hwan Chang, Laura M. Heiser, Daniel M. Zuckerman 601-Pos Board B425 MACHINE LEARNING BASED OPTIMIZATION TO SIMULATE TUMOR DE - VELOpmENT. Julian M. Herold , Eric Behle, Alexander H. Schug 602-Pos Board B426 MACHINE LEARNING COMPUTATIONAL TOOL AND HEMODYNAMIC SOLVER FOR PREDICTING ALTERATIONS OF VESSELS PRESSURE IN LUPUS DISEASE. Dragana Savic , Yasser Aboelkassem 603-Pos Board B427 EXPERIMENTAL AND THEORETICAL MODELS OF PARASYSTOLE. Khady Diagne , Thomas M. Bury, Leon Glass, Gil Bub 604-Pos Board B428 A MULTISCALE MODEL OF THE CARDIOVASCULAR SYSTEM THAT INCOR - PORATES BAROREFLEX CONTROL OF CHRONOTROPISM, CELL-LEVEL CONTRACTILITY, AND VASCULAR TONE. Kenneth S. Campbell , Hossein Sharifi, Jonathan F. Wenk 605-Pos Board B429 ROLE OF ATP SUPPLY IN LIMITING RESERVE CARDIAC POWER OUT - PUT. Rachel Lopez , Bahador Marzban, Filip Jezek, E. Benjamin Randall, Daniel A. Beard 606 -Pos Board B430 ENERGETIC DEPLETION AND KCNE1 MUTATIONS DESTABILIZE POTASSIUM TRANSPORT ACROSS EPITHELIAL LAYERS IN THE INNER EAR. Julia Lasater, Robert M. Raphael 607 -Pos Board B431 WHO TAKES MY CALCIUM? DIFFUSIONAL MODEL AND EXPERIMENTAL INSIGHTS ON INTRA- AND EXTRA- CELLULAR CALCIUM FLUXES IN PARV - ALBUMIN KNOCK-OUT MICE. Lorenzo Marcucci , Marta Canato, Simona Boncompagni, Feliciano Protasi, Carlo Reggiani 608 -Pos Board B432 FUNDAMENTAL CELL BEHAVIOR EMERGES FROMWHOLE CELL SIMU - LATIONS OF A MINIMAL CELL BY INTEGRATING EXPERIMENT AND THEORY. Zane R. Thornburg , David Bianchi, Troy A. Brier, Benjamin R. Gilbert, Tyler M. Earnest, Marcelo Cardoso dos Reis Melo, Andras Cook, Kim S. Wise, Hamilton O. Smith, Clyde A. Hutchison III, John I. Glass, Zaida Luthey-Schulten 609-Pos Board B433 INTEGRATED WHOLE-CELL GEOMETRIC MODELING OF ORGANELLE INTERACTIONS IN S. CEREVISIAE. Mary Mirvis , Wallace Marshall 610-Pos Board B434 ZEBRAFISH AIRINEMES OPTIMIZE BETWEEN BALLISTIC SEARCH AND DIF - FUSIVE SEARCH. Sohyeon Park , Hyunjoong Kim, Yi Wang, Dae Seok Eom, Jun F. Allard 611-Pos Board B435 DYNAMIC INSTABILITY OF DENDRITIC TIPS GENERATES COMPLEX NEURO - NAL MORPHOLOGIES. Sabyasachi Sutradhar , Sonal Shree, Olivier Trottier, Yuhai Tu, xin liang, Jonathon Howard

F R I D A Y

S U N D A Y

44