Biophysical Society 66th Annual Meeting Program Guide

Monday, February 21

703-Symp 9:45 am REPROGRAMMING OF MITOCHONDRIA BY PROTEOLYSIS. Thomas Langer Platform Protein Dynamics and Allostery I 8:15 am - 10:15 am, South, Level Two, Room 201/202/203 Co-Chairs Wonmuk Hwang, Texas A&M University, USA Giulia Palermo, University of California, Riverside, USA 704-Plat 8:15 am ALLOSTERIC REGULATION OF PROTEIN KINASE A BY NUCLEOTIDES AND METAL IONS. Lihui Bai , Yaojun Zhang, Jenny England, Lydia Good, Rodrigo A. Maillard 705-Plat 8:30 am REVEALING THE ALLOSTERIC PATHWAYS OF THE PROTEIN-TYROSINE PHOSPHATASE 1B: A COMBINED MUTAGENESIS-COMPUTATIONAL STUDY. Jinchan Liu , Emma Wang, Joseph P. Loria, Victor S. Batista 706 -Plat 8:45 am INSIGHT INTO SAMHD1 REGULATION MECHANISM USING MOLECULAR DYNAMICS SIMULATIONS. Gauri T. Thapa 707 -Plat 9:00 am THERMODYNAMIC AND ALLOSTERIC BASIS OF PARADOXICAL ACTIVA - TION IN V600E BRAF CANCERS. Damien Rasmussen , Manny Semonis, Nicholas Levinson 708 -Plat 9:15 am ATOMISTIC ORIGIN FOR CATCH BOND FORMATION IN THE PRETCR- pmHC COMPLEX. Wonmuk Hwang , Robert J. Mallis, Matthew J. Lang, Ellis L. Reinherz 709-Plat 9:30 am Travel Award Winner LOAD-DEPENDENT CONFORMATIONAL BEHAVIOR OF THE A6 TCR HLA-A2/TAX pmHC COMPLEX. Ana C. Chang-Gonzalez , Robert J. Mallis, Matthew J. Lang, Ellis L. Reinherz, Wonmuk Hwang 710-Plat 9:45 am LONG-LIVED CONFORMATIONAL CHANGES IN ACTIVE GSΑ REVEALED IN ATOMISTIC DETAIL BY INTEGRATING HDX-MS WITH ENHANCED MO - LECULAR DYNAMICS SIMULATIONS. Davide Provasi , Aleksandar Spasic, Nguyen Minh Duc, Yang Du, Donghoon Ahn, Jun Xu, KaYoung Chung, Marta Filizola 711-Plat 10:00 am ESTABLISHING THE ALLOSTERIC MECHANISM IN CRISPR-CAS9. Giulia Palermo Platform Liquid-Liquid Phase Separation I 8:15 am - 10:15 am, South, Level Two, Room 204/205/206 Co-Chairs Loren Hough, University of Colorado Boulder, USA Riley Workman, University of Texas Medical Branch at Galveston, USA 712-Plat 8:15 am LIQUID-LIKE PROTEIN INTERACTIONS IN FAST ENDOPHILIN MEDIATED ENDOCYTOSIS. Caleb Walker 713-Plat 8:30 am INCORPORATION AND ASSEMBLY OF A LIGHT-EMITTING ENZYMATIC RE - ACTION INTO MODEL PROTEIN CONDENSATES. Muyang Guan , Mikael V. Garabedian, Marcel Leutenegger, Benjamin S. Schuster, Matthew C. Good, Daniel A. Hammer

M O N D A Y

Graduate Student Breakfast 7:30 am - 8:30 am, Esplanade, Room 155

Support contributed by the Burroughs Wellcome Fund. This breakfast presents an opportunity for graduate student Annual Meeting attendees to meet and discuss the issues they face in their cur - rent career stage. Limited to the first 100 attendees. Registration/Exhibitor Registration 7:30 am - 5:00 pm, South Lobby Poster Viewing 8:00 am - 10:00 pm, Exhibit Hall ABC Symposium Mechanosensation 8:15 am - 10:15 am, South, Level Three, Room 301/302 Chair Verena Ruprecht, Centre for Genomic Regulation, Spain 697-Symp 8:15 am COLLECTIVELY MIGRATING BORDER CELS INTEGRATE PHYSICAL, CHEMI - CAL AND ADHESIVE CUES TO CHOOSE A PATH. Denise Montell , Wei N. Dai, Xiaoran Guo, Joseph Campanale, James A. Mondo, Allison Gabbert 698-Symp 8:45 am FROM CANCER TO CULTURED MEAT: DEVELOPING TECHNOLOGIES TO UNDERSTAND AND HARNESS CELLULAR MECHANOSENSATION. Amy Rowat 699-Symp 9:15 am ACTIVE DYNAMICS AND TUNABLE MECHANICS OF ACTIN-MICROTU - BULE COMPOSITES. Rae M. Robertson-Anderson No Abstract 9:45 am EXPLORING FUNCTIONS OF THE NUCLEUS AS A MECHANO-CONTROL - LER OF ADAPTIVE CELL BEHAVIOUR. Verena Ruprecht Symposium Mitochondrial Plasticity in Health and Disease 8:15 am - 10:15 am, South, Level Three, Room 303/304 Chair Thomas Langer, Max Planck Institute for Biology of Ageing, Germany 700 -Symp 8:15 am MITOCHONDRIAL DIVISION GEOMETRY AND FATE. Suliana Manley 701-Symp 8:45 am BIOPHYSICAL MECHANISMS OF CONDITION-DEPENDENT MRNA LOCAL - IZATION TO THE MITOCHONDRIA. Brian M. Zid , Ximena Garcia Arceo, Tatsuhisa Tsuboi, Aidan I. Brown, Elena F. Koslover 702-Symp 9:15 am MITOCHONDRIAL F1FO ATP SYNTHASE DETERMINES THE LOCAL PRO - TON MOTIVE FORCE AT CRISTAE RIMS. Karin B. Busch , Bettina Rieger, Tasnim Arroum, Marie-Theres Borowski, Jimmy Villalta

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