Biophysical Society 66th Annual Meeting Program Guide

726-Plat 9:45 am COMBINED USE OF SERIAL BLOCK FACE SEM AND FOCUSED ION BEAM SEM ELUCIDATES THE 3D ULTRASTRUCTURE OF BLOOD PLATELETS AND THROM - BI. Maria A. Aronova, Denzel R. Cruz, Douglas J. Palumbo, Rahul R. Akkem, Zeyad A. Emam, Matthew D. Guay, Sung W. Rhee, Irina D. Pokrovskaya, Brian Storrie, Richard D. Leapman 727-Plat 10:00 am INTEGRATED LIGHT AND ELECTRON MICROSCOPY CONTINUUM RESOLU - TION IMAGING OF 3D CELL CULTURES. Edoardo Dimprima , Marta Garcia Montero, Sylwia Gawrzak, Paolo Ronchi, Ievgeniia Zagoriy, Yannick Schwab, Martin Jechlinger, Julia Mahamid Platform Membrane Receptors and Signal Transduction 8:15 am - 10:15 am, South, Level Two, Room 209/210/211 Co-Chairs Jun Allard, University of California, Irvine, USA YingJie Sun, Harvard University, USA 728-Plat 8:15 am CYTOPLASMIC ORGANIZATION MODULATES REACTION KINETICS IN CELLS. William Y.C. Huang , Xianrui Cheng, James E. Ferrell 729-Plat 8:30 am USING CHANNEL THEORY TO MODEL BIOCHEMICAL NETWORKS WITH FEED - BACK. Rebecca J. Rousseau 730-Plat 8:45 am WEIGHTED ENSEMBLE SIMULATION OF KINETIC SEGREGATION SHOWS ROLE OF OLIGOMERS AND CLOSE CONTACTS. Robert Taylor , Jun F. Allard, Elizabeth Read 731-Plat 9:00 am USING MICRORESONATORS TO SIMULTANEOUSLY MONITOR MASS AND AD - HESION OF SINGLE LIVING CELLS. Ilaria Incaviglia , Sophie Herzog, Upnishad Sharma, Gotthold Fläschner, Reinhard Fässler, Nico Strohmeyer, Daniel J. Müller 732-Plat 9:15 am PRKC KINASE MODULATES MREB FILAMENT AND BACTERIA GROWTH BY MONITORING CELL WALL PRECURSOR LIPID II. YingJie Sun , Ethan Garner 733-Plat 9:30 am SENSING THE SPATIAL RESOLUTION LIMIT OF PHAGOCYTOSIS. Manuel Eisentraut , Adal Sabri, Holger Kress 734-Plat 9:45 am IMAGING T-CELL ACTIVATION: TOPOGRAPHY AND FEATURES OF EARLY T-CELL CONTACTS. Markus Körbel , Edward Jenkins, James T. McColl, Caitlin O'Brien-Ball, Anna H. Lippert, Ana Mafalda Santos, Steven F. Lee, Simon J. Davis, David Klenerman 735-Plat 10:00 am Travel Award Winner ANALYSIS OF PI(4,5) P 2 METABOLISM FROM THE PERSPECTIVE OF DIFFER - ENT CELL TYPES. Lizbeth de la Cruz , Christopher Kushmerick, Jane Sullivan, Martin Kruse, Oscar Vivas Platform Biomaterials and Nanotechnology 8:15 am - 10:15 am, South, Level Two, Room 212/213/214 Co-Chairs Ido Levin, University of Washington, USA Keith Whitener, Naval Research Laboratory, USA

714-Plat 8:45 am MOLECULAR BASIS OF STRESS-TRIGGERED PHASE SEPARATION OF PAB1 MEDIATED BY FOLDED DOMAINS RATHER THAN DISORDERED REGIONS. Ruofan Chen , Julia Shangguan, Darren N. Kahan, Joshua A. Riback, D. A. Drummond, Tobin R. Sosnick 715-Plat 9:00 am MECHANISTIC INSIGHTS INTO THE PROMOTION OR INHIBITION OF PHASE SEPARATION BY POLYUBIQUITIN CHAINS OF DIFFERENT LINKAG - ES. Carlos A. Castaneda , Thuy P. Dao, Yiran Yang, Sarasi K.K. Galagedera 716-Plat 9:15 am DEFINING PROTEIN CHARACTERISTICS THAT DRIVE PHASE SEPARATION. Ayyam Ibrahim, Nathan Khaodeuanepheng, Elisi Paiz, Jeffre Allen, John J. Correia, Nicholas Fitzkee, Karen Lewis, Steven Whitten, Loren E. Hough 717-Plat 9:30 am MESOSCOPIC ORGANIZATION OF BIOMOLECULAR CONDENSATES. Omar Adame-Arana , Gaurav BAJPAI, Samuel A. Safran 718-Plat 9:45 am Travel Award Winner TAU BIOMOLECULAR CONDENSATES EXHIBIT LENGTH SCALE DEPEN - DENT AGING. Rachel S. Fisher , Shana Elbaum-Garfinkle 719-Plat 10:00 am EFFECT OF CYCLIZATION ON THE LIQUID-LIQUID PHASE SEPARATION OF PENTAGLYCINE. Riley J. Workman , B. Montgomery Pettitt Platform Electron Microscopy and Scattering Techniques 8:15 am - 10:15 am, South, Level Two, Room 207/208 Co-Chairs Travel Award Winner DEEP LEARNING-BASED PREDICTION OF ELECTRON DENSITY MAPS OF PROTEINS. Tom Pan, Shikai Jin , Mitchell D. Miller, George N. Phillips 721-Plat 8:30 am INTRODUCING THE CANDOR POLYCHROMATIC REFLECTOMETER FOR STRUCTURAL BIOLOGY APPLICATIONS. David P. Hoogerheide 722-Plat 8:45 am UNSUPERVISED LEARNING APPROACH FOR MAPPING OF PATHOLOGI - CAL LESIONS IN X-RAY SCANNING MICRODIFFRACTION STUDIES OF AL - ZHEIMER’S DISEASE. Abdullah Al Bashit , Prakash Nepal, Lee Makowski 723-Plat 9:00 am EFFECTS OF CRYO-EM COOLING ON STRUCTURAL ENSEMBLES. Lars V. Bock , Helmut Grubmuller 724-Plat 9:15 am MOLECULAR MECHANISM OF STRESS-INDUCED REACTIVATION IN MUMPS VIRUS CONDENSATES. Xiaojie Zhang , Sindhuja Sridharan, Iev - geniia Zagoriy, Christina Eugster Oegema, Cyan Ching, Tim Pflaesterer, Herman K. H. Fung, Ina Poser, Christoph W. Müller, Anthony A. Hyman, Mikhail M. Savitski, Julia Mahamid 725-Plat 9:30 am SPINDLE-SHAPED ARCHAEAL VIRUSES EVOLVED FROM ROD-SHAPED ANCESTORS TO PACKAGE A LARGER GENOME. Fengbin Wang , Virginija Cvirkaite-Krupovic, Matthijn Vos, Leticia Beltran, Jun Liu, Mart Krupovic, Edward H. Egelman Fengbin Wang, University of Virginia, USA Xiaojie Zhang, EMBL Heidelberg, Germany 720-Plat 8:15 am

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