Program Book

2151-P lat 10:00 am CELL DIVISIONS CAUSE LONG-RANGE WELL-ORDERED VORTICITY PATTERNS IN ENDOTHELIAL TISSUE. Ninna S. Rossen, Jens M. Tarp, Joachim Mathiesen, Mogens H. Jensen, Lene Oddershede

2161-P lat

8:30 am

cpow travel awardee SOMATIC MUTATIONS IN THE NA,K-ATPASE CAN CAUSE HYPERTENSION. Hanne Poulsen , Elena Azizan, Poul Nissen, Morris Brown 2162-P lat 8:45 am GLUTATHIONYLATION OF THE Β 1 SUBUNIT PREVENTS THE E1NA3 TO E2P FORWARD REACTION IN THE NA + , K + ATPASE. Alvaro Garcia , Chia-Chi Liu, Ronald Clarke, Helge Rasmussen 2163-P lat 9:00 am DISCOVERY OF ENZYME MODULATORS VIA HIGH- THROUGHPUT TIME-RESOLVED FRET IN LIVING CELLS. MOLECULAR BASIS FOR SODIUM VERSUS CALCIUM BINDING IN THE SODIUM-CALCIUM EXCHANGER. Fabrizio Marinelli , José D. Faraldo-Gómez 2165-P lat 9:30 am STRUCTURE OF TRIMERIC CALCIUM/PROTON ANTIPORTER PROTEIN YFKE REVEALS THE MECHANISMS OF CALCIUM EFFLUX AND ITS PH REGULATION. Lei Zheng 2166-P lat 9:45 am FUNCTIONAL RECONSTITUTION OF THE MITOCHONDRIAL CA 2+ /H + ANTIPORTER LETM1. Ming-Feng Tsai , Christopher Miller 2167-P lat 10:00 am FOLDING AND ASSOCIATION OF HUMAN UNCOUPLING PROTEIN-1 IN BIOLOGICAL MEMBRANES: EVIDENCE FOR MULTIMERIC FUNCTIONAL FORMS. Tuan Hoang , Matthew David Smith, Masoud Jelokhani-Niaraki 8:15 am –10:15 am , R oom 304 Platform Protein-Nucleic Acid Interactions II Co-Chairs Mark Williams, Northeastern University Fredrik Westerlund, Chalmers University of Technology, Sweden 2168-P lat 8:15 am PROBING PHYSICAL PROPERTIES OF A DNA-PROTEIN COMPLEX USING NANOFLUIDIC CHANNELS. Karolin Frykholm, Mohammadreza Alizadehheidari, Joachim Fritzsche, Jens Wigenius, Philip Nevin, Joshua Araya, Penny Beuning, Mauro Modesti, Fredrik Persson, Fredrik Westerlund 2169-P lat 8:30 am DYNAMICS OF NAP1-ASSISTED NUCLEOSOME ASSEMBLY IMAGED WITH HIGH-SPEED ATOMIC FORCE MICROSCOPY. Allard Katan , Rifka Hoogeboom-Vlijm, Alexandra Lusser, Cees Dekker 2170-P lat 8:45 am CHARACTERIZING THE STRUCTURE AND FUNCTION OF THE N-TERMINUS OF SCHIZOSACCHAROMYCES POMBE CDC5, A PRE-MRNA SPLICING FACTOR. Scott E. Collier , Dungeng Peng, Markus Voehler, Nicholas Reiter, Melanie Ohi 2171-P lat 9:00 am CONDENSATION OF DNA MEDIATED BY THE BACTERIAL CENTROMERE BINDING PROTEIN SPO0J/PARB. Cesar L. Pastrana, James A. Taylor, Mark S. Dillingham, Fernando Moreno-Herrero Simon J. Gruber , Razvan L. Cornea, Kurt C. Peterson, Gregory D. Gillispie, Seth L. Robia, David D. Thomas 2164-P lat 9:15 am

T U

8:15 am –10:15 am , R oom 132/133 Platform Intrinsically Disordered Proteins

E S

Co-Chairs Birthe Kragelund, University of Copenhagen, Denmark Trevor Creamer, University of Kentucky 2152-P lat 8:15 am PREDICTION OF THE EFFECTS OF THE VAL66MET POLYMORPHISM ON THE CONFORMATIONAL ENSEMBLE OF AN INTRINSICALLY DISORDERED PROTEIN, BRAIN-DERIVED NEUROTROPHIC FACTOR. Ruchi Lohia , Reza Salari, Grace Brannigan 2153-P lat 8:30 am HOW DO INTERACTIONS IN CIS WITH ORDERED DOMAINS INFLUENCE SEQUENCE-ENSEMBLE RELATIONSHIPS OF INTRINSICALLY DISORDERED REGIONS? Anuradha Mittal , Kanchan Garai, Rohit V. Pappu 2154-P lat 8:45 am THE C-TERMINAL V5 DOMAIN OF PROTEIN KINASE C α IS A MULTI-FUNCTIONAL INTRINSICALLY DISORDERED PROTEIN MODULE. Yuan Yang , Tatyana I. Igumenova 2155-P lat 9:00 am C-TERMINAL ERK D- (AND F-LIKE) DOMAINS LINKTHE NA + /H + EXCHANGER NHE1 TO ERK2 PHOSPHORYLATION AND REGULATION VIA SCAFFOLDING. Ruth Hendus-Altenberger, Jeff Schnell, Elena Pedraz, Jonas Marstrand Lacour, Jane Johansen, Stine F. Pedersen, Birthe B. Kragelund 2156-P lat 9:15 am SPEED DATING WITH KIX: A SINGLE DOMAIN THAT HAS MANY PARTNERS. Sarah L. Shammas , Jane Clarke 2157-P lat 9:30 am MOLECULAR SIMULATIONS OF THE DYNAMICS OF DISORDEREDPROTEINS. W. Wendell Smith , Po-Yi Ho, Elizabeth Rhoades, Corey O’Hern 2158-P lat 9:45 am THE PROTECTIONOFMEMBRANES FROMCOLD-STRESS: A STRUCTURAL STUDYOFTHE INTRINSICALLY DISORDERED DEHYDRINBOUNDTOMICELLES AND LIPOSOMES. Steffen P. Graether , Matthew Clarke, JosephineWarnica, John Atkinson, Jeffrey Madge 2159-P lat 10:00 am TRANSIENT DISORDER: CALCINEURIN AS AN EXAMPLE. Trevor P. Creamer , Tori B. Dunlap, Erik C. Cook

D A Y

8:15 am –10:15 am , R oom 303 Platform Membrane Pumps, Transporters, and Exchangers II

Co-Chairs Hanne Poulsen, University of Aarhus, Denmark Lei Zheng, University of Texas Houston Medical School 2160-P lat 8:15 am TRANSPORT PATHWAY IN CU + P-TYPE ATPASES. Magnus Andersson , Daniel Mattle, Oleg Sitsel, Anna Marie Nielsen, Erik Lindahl, Stephen H. White, Poul Nissen, Pontus Gourdon

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Biophysical Society 58 th Annual Meeting, San Francisco, California