BPS2025 Full Program

Platform Protein Structure and Conformation II 4:00 pm - 6:00 pm, Room 502A

Platform From Transcription to the Three R’s 4:00 pm - 6:00 pm, Room 502B

M O N D A Y

Co-Chairs Melike Berksöz, Sabanci University, Turkey Wolfgang Peti, University of Connecticut Health Center, USA 954-Plat 4:00 pm MOLECULAR MECHANISM OF CASPASE-9 CARD OLIGOMERIZATION USING CRYO-EM AND NMR SPECTROSCOPY. Swasti Rawal , Stefan Bohn, Dagmar Kolb, Tea Pavkov-Keller, Ambroise Desfosses, Tobias Madl, T. Reid Alderson 955-Plat 4:15 pm CAPTURING OLIGOMERIC STATES OF LON PROTEASE INVOLVED IN ITS REGULATION. Ishan Rathore , Alla Gustchina, Di Zhang, Jeffrey Mind rebo, Arsen Kudzhaev, Anna Andrianova, Tatyana Rotanova, Gabriel C. Lander, Alexander Wlodawer 956-Plat 4:30 pm BY DECODING HOW PP2A:B55 CONTROLS MITOSIS, WE UNDERSTAND HOW IT RECRUITS SUBSTRATES. Wolfgang Peti , Rebecca Page 957-Plat 4:45 pm STRUCTURE QUANTIZATION ENABLES ULTRA-FAST PREDICTION OF PRO TEIN CONFORMATIONAL FLEXIBILITY. Samuel Sledzieski , Pilar Cossio, Olga Troyanskaya, Sonya M. Hanson 958-Plat 5:00 pm SOLUTION TO THE HYDRATION PROBLEM. Patrick J. Fleming , John J. Correia, Karen G. Fleming 959-Plat 5:15 pm RATIONAL DESIGN OF CALMODULIN-BASED CALCIUM BIOSENSORS: IN SIGHTS FROM MOLECULAR DYNAMICS SIMULATIONS. Melike Berksöz 960-Plat 5:30 pm LIGHT-INDUCED CHANGES IN PROTEIN DYNAMICS OF PIGEON CRY4: INSIGHTS INTO MAGNETORECEPTION. Gargi S. Jagdale , Alan Pham, S. Wyatt Guy, Anthony T. Iavarone, Adam R. Offenbacher, Judith P. Klinman 961-FlashTalk 5:45 pm Canceled THE DYNAMICS OF THE ARF GAP ASAP1 SUPPORT A MEDIEVAL FLAIL MODEL FOR ARF GAP ACTIVITY. Eric M. Rosenberg , Olivier Soubias, Maxwell B. Watkins, Jesse B. Hopkins, Anthony M. Ciancone, Alexan der J. Sodt, Rebekah A. Jackson, Sandeep Pallikkuth, Francis J. O’Reilly, Andrew Byrd, Paul A. Randazzo 962-FlashTalk 5:50 pm REVERSIBLE OLIGOMERIZATION MEDIATED BY SMALL RNA BINDING IN A BACTERIAL ANTI-PHAGE SYSTEM. Kate Radford , Anton Kuzmenko, Anastasiya Oguienko, Tsui-Fen Chou, Alexei Aravin 963-FlashTalk 5:55 pm IMPROVED MODELING OF WATER MOLECULES IN MULTICONFORMER X-RAY MODELING. Stephanie Wankowicz

Co-Chairs Gabriella Chua, The Rockefeller University, USA Craig Martin, University of Massachusetts Amherst, USA 964-Plat 4:00 pm

NON-CATALYTIC FUNCTIONS OF RFC AND FEN1 MODULATE PCNA MEDIATED DNA SYNTHESIS. Gabriella N. Chua , Emily C. Beckwitt, Bryce J. Katch, John W. Watters, Kaitlin Abrantes, Ryogo Funabiki, Michael O’Donnell, Shixin Liu 965-Plat 4:15 pm Travel Award Winner REGULATION OF HELICASE ACTIVITY IN LONG-RANGE DNA END RESEC TION. Martin Mütze , Maria Rosaria Dello Stritto, Ilaria Ceppi, Petr Cejka, Ralf Seidel 966-Plat 4:30 pm COHESIN LOOP EXTRUSION REGULATES CHROMATIN SCANNING DUR ING HOMOLOGY SEARCH. Adam Rybczynski , Alberto Marin-Gonzalez, Namrata Nilavar, Daniel Nguyen, Ralph Scully, Taekjip Ha 967-Plat 4:45 pm SINGLE-MOLECULE STUDY OF THE ROLE OF LONG NON-CODING RNAS IN THE REPAIR OF THE DNA DOUBLE-STRAND BREAKS BY NON-HOMOL OGOUS END JOINING. Andela Radovanovic , Fianzo C. Smith-Clarke, Jinglong Wang, Roopa Thapar, Marc Nadal, Terence R. Strick 968-Plat 5:00 pm HERPES SIMPLEX VIRUS TYPE 1 ORIGIN BINDING PROTEIN UL9 TETHERS AND LOOPS ORIGIN- AND NON-ORIGIN DNA. Anita F. Meier , David S. Rueda 969-Plat 5:15 pm DYNAMIC POSITIONING OF TFIIE-RELATED WINGED-HELIX-DOMAIN IN RNA POLYMERASE III ELONGATION COMPLEX UNDERPINS ITS MULTI FUNCTIONALITY. Wei-Hau Chang 970-Plat 5:30 pm T7 RNA POLYMERASE - FUNDAMENTAL PRINCIPLES DRIVE UTILITY. Craig T. Martin , Ruptanu Banerjee, Amin Abek, Purnima Mala, Khiem Le, Sonu Kizhakkepura, Diwakaran Rathinam Palaniswamy, Sarah Perry 971-FlashTalk 5:45 pm MECHANISMS AND CONSEQUENCES OF RNA DUPLEX FORMATION WITHIN THE EXIT CHANNEL OF RNA POLYMERASES. Junqiao Zhu , Mi chael Z. Palo, Robert Landick, Aaron A. Hoskins 972-FlashTalk 5:50 pm CORRELATING CRX ACTIVATION DOMAIN ENSEMBLES WITH GENE EXPRESSION LEVELS. Eduardo Flores 973-FlashTalk 5:55 pm SINGLE-MOLECULE MEASUREMENTS REVEAL THE DYNAMICS OF HU MAN MITOCHONDRIAL TRANSCRIPTION INITIATION. Seung-Won Lee , Hajin Kim Platform Modelling, Mapping and Measuring in Systems Biology 4:00 pm - 6:00 pm, Room 501ABC Co-Chairs Bela Joos, University of Ottawa, Canada Daniel Zuckerman, Oregon Health and Science University, USA

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