BPS2025 Full Program

216-FlashTalk 5:55 pm DNAHX: A NOVEL, NON-MOTILE DYNEIN FAMILY IDENTIFIED BY CRYO EM, ENDOGENOUSLY. Diego Suchenski Loustaunau , Pengxin Chai, Kai Zhang PI to PI Mixer 4:00 pm - 6:00 pm, Room 402AB Engage in meaningful one-on-one discussions with col¬leagues and exchange insights on navigating the challenges between landing your job and securing your next promotion. Connect with other PIs to share strategies for managing lab staff, getting your research published, renewing funding, and building a strong professional network that sup ports your career advancement. Primarily Undergraduate Institutions (PUI) Network Annual Meeting Mixer 5:00 pm - 7:00 pm, Room 403A Are you interested in or currently building your career at a Primarily Undergraduate Institution (PUI)? Would you like to meet and learn from biophysicists at PUIs around the world? Then join us at the Annual Meeting for the PUI Network Annual Meeting Mixer! Here you’ll have the opportunity to meet with a diverse group of PUI professors to learn, discuss, and share ideas related to your career at a PUI. We hope to see you there! Korean Biophysicists Meeting 5:30 pm - 6:00 pm, Room 408A Exhibitor Presentation LUMICKS 5:30 pm - 7:00 pm, Room 404AB Democratizing Dynamic Single Molecule Analysis: Advancing Biological Understanding through C-Trap™ Technology and Showcasing Discover ies from Early-Career Scientists Dynamic single-molecule research has revolutionized our understand ing of biology by providing crucial insights into key molecular and cellular mechanisms, such as DNA repair, protein dynamics, and phase separation processes, among others. However, this field of science has traditionally been accessible only to experts capable of building and op erating complex home-built instruments, able to produce specific DNA or protein samples, and developing sophisticated algorithms for correct single-molecule data analysis and interpretation. To democratize access to single-molecule technologies, LUMICKS introduced the C-Trap™ as the first instrument of its kind which uniquely combines optical tweezers, single-molecule fluorescence, and auto mated microfluidics. This combination allows the correlation of single molecule force and fluorescence measurements in real-time to enable the investigation of dynamic molecular mechanisms with a ready-to-go instrument. Here, we will introduce the C-Trap™, look forward to future develop ments continuing the democratization of the technology, and also look back on the last year and celebrate impactful dynamic single molecule science from the last year. We will also provide a platform for two early-career scientists to share their exciting work using the C-Trap™. Kacey Mersch, a post-doc from the Lohman lab at WUSTL, will pres ent and discuss his work titled “Single stranded DNA translocation and DNA helicase activities of Mycobacterium tuberculosis UvrD1 Dimers”. This work utilizes the unique capabilities of the C-Trap™ to dissect the

mechanism of a dimeric UvrD-family helicase (UvrD1). Yukun Wang, a postdoc from the Laboratory of Nanoscale Biophysics and Biochemistry at Rockefeller University, will present and discuss his work titled “Using the C-Trap™ technology to visualize eukaryotic transcription at the single-molecule level” where the C-Trap™ enables directly measuring details of the transcription process that have been elusive with bulk measurements. Join us to learn more about dynamic single molecule science, future C-Trap™ developments, and for a celebration of single molecule science from the last year! Speakers Kacey Mersch, Postdoctoral Scholar, Washington University St. Louis Trey Simpson, Principal Scientist, LUMICKS Yukun Wang, Postdoctoral Scholar, The Rockefeller University Dinner Meet-Ups 6:00 pm - 6:30 pm, West Lobby/Society Booth Interested in making new acquaintances and experiencing the cuisine of Los Angeles? Meet at the Society Booth each evening Sunday through Tuesday at 6:00 PM, where a BPS member will coordinate dinner at a local restaurant. In addition to the general Dinner Meet-Up groups, there will be addi tional meet-ups for different groups and focus topics. Additional groups may be added, and dates may be subject to change. Check the app for the latest information. Attendees are responsible for covering their individual expenses. Student Research Achievement Award (SRAA) Poster Competition 6:00 pm - 9:00 pm, West Exhibit Hall This session features graduate, masters and PhD students who are presenting posters at the Annual Meeting. During the competition, stu dents will deliver a five-minute oral presentation of their poster to one or more judges. Winners will be recognized on Monday evening prior to the Biophysical Society Lecture. BPS Publications Dinner 7:00 pm - 10:00 pm, Mastro’s Ocean Club

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