BPS2025 Full Program

295-Pos Board B79 PROBING THE ALLOSTERIC NETWORK OF THE CLPB DISAGGRE GASE. Zhaocheng Zhang , Ashan Dayananda, Krishan Walpalage, Gilad Haran, George Stan 296-Pos Board B80 THE FUNCTIONAL ROLE OF THE FXR HINGE IN TRANSCRIPTIONAL REGULATION. Arumay Biswas , Elise Wang, Valerie Ledford, Jordan A. Wenning, Denise Okafor 297-Pos Board B81 Travel Award Winner ANTICOOPERATIVE SUBSTRATE BINDING IN THE YEAST BC1 COM PLEX. Zahra Moradi , Sophia M. Gross, Spencer B. Grewe, Oleksandr Kokhan 298-Pos Board B82 GENERALIZATION OF FLUCTUATION-DISSIPATION RELATION ENABLES PREDICTIVE AND OPTIMAL ENHANCED SAMPLING OF PROTEIN CON FORMATIONAL STATES AND TRANSITIONS. Huiyu Li , Ao Ma 299-Pos Board B83 UNRAVELING TEMPERATURE-INDUCED CONFORMATIONAL DYNAM ICS IN HTADH USING TDHDX-MS. Kotchakorn T.sriwong , Pankaj Dubey, Anthony T. Iavarone, Susan M. Miller, Judith P. Klinman 300-Pos Board B84 COVALENT ATTACHMENT OF SITE SPECIFIC PHOTOACTIVE-HEAT TRANSFER PROBES TO TEST MODELS OF LONG RANGE, LOCAL HEATING IN SOYBEAN LIPOXYGENASE. Sabyasachi Sarkar , Anthony T. Iavarone, Judith P. Klinman Membrane Protein Structures I (Boards B85 - B111) 301-Pos Board B85 PHOSPHOLIPID HEADGROUPS REGULATE P-GLYCOPROTEIN DOSE RESPONSE CURVES IN THE PRESENCE OF THE CARDIOVASCULAR DRUG VERAPAMIL. Nghi Tran , Nghi Tran 302-Pos Board B86 STRUCTURAL AND FUNCTIONAL INSIGHTS INTO LPD-3 MEDIATED BULK LIPID TRANSPORT. Hannah Long 303-Pos Board B87 RETINAL FLEXIBILITY IN ACTIVE RHODOPSIN UNCOVERED BY SOLID STATE 2 H NMR AND QM/MM SIMULATIONS. Andrey V. Struts , Xiaolin Xu, Trivikram R. Molugu, Suchithranga M.D.C. Perera, Charitha Guruge, Samira Faylough, Carolina L. Nascimento, Nasri Nesnas, Mikhail N. Ryazantsev, Michael F. Brown 304-Pos Board B88 STRUCTURAL PREDICTION AND LIGAND INTERACTION OF HUMAN BITTER TASTE RECEPTOR TAS2R50, A POTENTIAL THERAPEUTIC TARGET FOR CARDIOVASCULAR DISEASES. Yixin C. Xu , Soo-Kyung Kim, William A. Goddard 305-Pos Board B89 STRUCTURAL BASIS OF POTASSIUM SELECTIVITY IN KALIUM CHANNEL RHODOPSINS. Seiya Tajima , Yoon Seok Kim, YoungJu Jo, Peter Y. Wang, Joseph M. Paggi, Charu Ramakrishnan, Shunki Takaramoto, Takashi Nagata, Masae Konnno, Kota Katayama, Hideki Kandori, Ron O. Dror, Keiichi Inoue, Karl Deisseroth, Hideaki Kato 306-Pos Board B90 Travel Award Winner BIOMEMBHUB: AN INNOVATIVE CYBERINFRASTRUCTURE FOR MEM BRANE PROTEIN RESEARCH. Alexey Kovalenko , Stanislav Cherepanov, L. Ponoop Prasad Patro, Zigang Song, Sang-Jun Park, Irina D. Pogozheva, Andrei L. Lomize, Wonpil Im

307-Pos Board B91 PROBING STRUCTURAL DYNAMICS OF KCNE3 WHILE INTERACTING WITH KCNQ1 IN A BILAYER MEMBRANE: A MOLECULAR DYNAMICS SIMULATION STUDY. Indra D. Sahu , Antonio J.F. Aguado, Anna Clara Moura, Daniel I. Oriaku, Ikponwmosa Obaseki, Steven Alston, Andrea Kravats, Charles R. Sanders, Gary A. Lorigan 308-Pos Board B92 MG 2+ ION CHANNEL CORA IN PATHOGENIC BACTERIA. Patrick O’Reilly , Peter R. Johnson, Fei Zhou, Doreen Matthies 309-Pos Board B93 UNDERSTANDING MEMBRANE RECOGNITION MECHANISMS OF ABHD5 PROTEIN. Amit Kumar , Christopher V. Kelly, James G. Granneman, Yu ming Huang 310-Pos Board B94 COMPUTATIONAL SIMULATIONS OF CYCLOTIDE SUPRAMOLECULAR COMPLEXES: SELF AGGREGATION AND AFFINITY WITH LIPID BILAY ERS. Neville Y. Forlemu , Simon M. Mwongela, Ajay Mallia, Sairam Board B95 TOWARDS STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A BACTERIAL MANGANESE EXPORTER. Paul-Pierre Boutet , Keiki V. Miller, Oliver Nicholson, Luisa Morgan, Shivani Ahuja 312-Pos Board B96 APPROACHES TO CHARACTERIZE IN SITU ARENAVIRUS GLYCOPROTEIN STRUCTURE AND FUNCTION. Lily Taylor , Aldo J. Munoz, James Zhen, Fred Jimenez, Hong Zhou, Jonathan Abraham, Jose A. Rodriguez 313-Pos Board B97 INVESTIGATING THE STRUCTURAL TOPOLOGY OF KCNE3 IN A MIMICKED VESICLE ENVIRONMENT USING ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY. Draven B. Reynolds , Conner Campbell, Matthew Scheyer, Patrick Williams, Kayla Hamilton, Patricia Loka, Zoe Warri, Beyza Bektasoglu, Charles R. Sanders, Gary A. Lorigan, Indra D. Sahu 314-Pos Board B98 MYCOBACTERIUM TUBERCULOSIS CRGA FORMS A DIMERIC STRUCTURE WITH ITS TRANSMEMBRANE DOMAIN SANDWICHED BETWEEN CYTO PLASMIC AND PERIPLASMIC B-SHEETS, ENABLING MULTIPLE INTERAC TIONS WITH OTHER DIVISOME PROTEINS. Yiseul Shin, Ramesh Prasad , Nabanita Das, Joshua A. Taylor, Huajun Qin, Xiaoling Leng, Martin Hu, Yan-Yan Hu, Riqiang Fu, Rongfu Zhang, Huan-Xiang Zhou, Timothy A. Cross 315-Pos Board B99 STRUCTURAL ANALYSIS OF HUMAN ENDOGENOUS RETROVIRUS K (HERV-K) ENVELOPE PROTEIN. Chen Sun , Jeremy Shek, Roshan R. Rajamanickam, Elise Wilson, Diptiben Parekh, Chitra Hariharan, Dawid S. Zyla, Kelly C. Shaffer, Ruben Diaz Avalos, Kathryn M. Hastie, Erica Ollmann Saphire, Stephanie Harkins 316-Pos Board B100 DEVELOPMENTS TOWARDS TIME-RESOLVED SMALL ANGLE X-RAY SCAT TERING FOR STUDYING GPCR ACTIVATION. Aleksey Raskovalov , Vadim Board B101 MOLECULAR MECHANISM OF FERROSOME FORMATION. Zhuqing Mao 318-Pos Board B102 ISOLATION OF SCARCE MEMBRANE PROTEIN COMPLEXES FROM C. ELEGANS . Joline N. Nguyen Tangirala 311-Pos Cherezov 317-Pos

F R I D A Y

S U N D A Y

32