BPS2025 Full Program

319-Pos Travel Award Winner TMEM63C CRYO-EM STRUCTURE INDICATES IT FUNCTIONS AS A MONO MER. Yuqi Qin 320-Pos Board B104 THE PH DOMAIN IN THE ARFGAP ASAP1 DRIVES CATALYTIC ACTIVATION THROUGH AN UNPRECEDENTED MECHANISM. Olivier Soubias , Samuel Foley, Xiaoying Jian, Rebekah Jackson, Eric Rosenberg, Margaret E. John son, Alexander J. Sodt, Paul Randazzo, Andrew Byrd 321-Pos Board B105 ALLOSTERIC MECHANISM OF MEMBRANE FUSION ACTIVATION IN A HERPESVIRUS. Gonzalo L. Gonzalez-Del Pino , Richard M. Walsh, Doina Atanasiu, Tina M. Cairns, Wan Ting Saw, Gary H. Cohen, Ekaterina Heldwein 322-Pos Board B106 NOVEL FINDINGS IN TOLQ-TOLR COMPLEX STRUCTURE. Elina Karimul lina , Yirui Guo, Hanif Muhammad Khan, Tabitha Emde, Zbyszek Otwin owski, Peter D. Tieleman, Dominika Borek, Alexei Savchenko 323-Pos Board B107 ASYMMETRY OF SINGLE-MOLECULE PARTITIONING AND TRAPPING IN THE AEROLYSIN PORE. Ishan Ghai, Jan C. Behrends 324-Pos Board B108 STRUCTURE OF MYCOBACTERIAL NDH-2 BOUND TO 2-MERCAPTO QUINAZOLINONE. Yingke Liang , Stephanie A. Bueler, Chen-yi Cheung, Gregory M. Cook, John Rubinstein 325-Pos Board B109 MOLECULAR DYNAMICS SIMULATIONS OF THE LIPID-II INTERACTIONS AND ASSEMBLY OF NISIN CHAINS IN BACTERIAL MEMBRANES. Hugo A. Perez , Bernard S. Gerstman, Prem P. Chapagain 326-Pos Board B110 EVOLUTIONARILY DIVERSE CAVEOLINS SHARE A COMMON STRUCTURAL FRAMEWORK BUILT AROUND AMPHIPATHIC DISCS. Sarah M. Connolly , Bing Han, Louis F.L. Wilson, Tyler S. Brant, Louise Chang, Darrin T. Schultz, Alican Gulsevin, Jens Meiler, Erkan Karakas, Shyamal Mosalaganti, Anne K. Kenworthy, Melanie D. Ohi 327-Pos Board B111 PEPTIDE-BASED DNA MODIFICATIONS FOR FORMATION OF NANO DISCS. Praneetha Sundar Prakash , Soumya Chandrasekhar, Thorsten Schmidt Intrinsically Disordered Proteins I (Boards B112 - B139) 328-Pos Board B112 A FLOCK OF COMPUTATIONAL METHODS FOR INVESTIGATING DISOR DERED PROTEIN REGIONS. Jeffrey M. Lotthammer , Garrett M. Ginell, Daniel Griffith, Borna Novak, Emery T. Usher, Ryan Emenecker, Alex S. Holehouse, Nick Razo, Stephen Plassmeyer 329-Pos Board B113 INTRINSICALLY DISORDERED PROTEIN (IDP) STRUCTURE PREDICTION USING THE HYBRID QUANTUM-CLASSICAL MODEL OF LSTM AND DIHEDRAL-ANGLE-BASED SAMPLING METHOD. Suhyun PARK, Sovan monynuth Heng, Sangwook Wu 330-Pos Board B114 STRUCTURAL AND FUNCTIONAL SIGNIFICANCE OF TRANSIENT INTERAC TIONS IN INTRINSICALLY DISORDERED PROTEINS. Samuel Wohl , Wenwei Zheng, Yishai Gilron Board B103

331-Pos Board B115 CHARACTERIZING OLIGOMERIC AMYLOID-Β42 AND POPC INTER ACTIONS THROUGH MOLECULAR DYNAMICS: A COMPUTATIONAL APPROACH FOR UNDERSTANDING ALZHEIMER’S DISEASE. Emma M. Cleveland , Kelsie M. King, Anne M. Brown 332-Pos Board B116 THE FUNCTION AND CONFORMATION OF PROTEIN DISORDERED REGIONS IS ENCODED IN THEIR MODULAR ARCHITECTURE. Debanjana Das , Matthew W. Parker 333-Pos Board B117 Travel Award Winner A DEEP LEARNING METHOD FOR PREDICTING INTERACTIONS FOR INTRINSICALLY DISORDERED PROTEINS. Kartik Majila 334-Pos Board B118 LOW COMPLEXITY POLYMERS - RELATIONS BETWEEN MICROPHASE, POLYMER COLLAPSE TRANSITION AND SEQUENCE. Martin Girard 335-Pos Board B119 A MEMBRANE-INSERTION CODE FOR INTRINSICALLY DISORDERED PRO TEINS. Fidha Nazreen Kunnath Muhammedkutty , Huan-Xiang Zhou 336-Pos Board B120 USING SINGLE MOLECULE SPECTROSCOPY TO PROBE NUCLEOCAPSID RNA INTERACTIONS. Madison Stringer , Jasmine Cubuk, J. Jeremias Incicco, Debjit Roy, Alec Garasimowicz, Melissa D. Stuchell-Brereton, Andrea Soranno 337-Pos Board B121 TRANSIENT NON-LOCAL INTERACTIONS DOMINATE THE DYNAMICS OF THE INTRINSICALLY DISORDERED C-TERMINAL OF PHOSPHATASE FCP1. Lillian Otteson , Samuel Wohl, Maximilian Riedel-Topper, Kevin Na mitz, Gerdenis Kodis, Wenwei Zheng, Scott A. Showalter, Sara M. Vaiana 338-Pos Board B122 INVESTIGATING THE INTRINSICALLY DISORDERED TRANSCRIPTION AC TIVATION DOMAIN OF NFΚB AND ITS IMPACT ON FUNCTION. Tristan R. Gunther , Hannah E.R. Baughman, Huishan Chen, Elizabeth A. Komives 339-Pos Board B123 MUTATIONS TO THE N-TERMINUS OF TAU ALTERS DRASTICALLY THE FORCE-RESPONSE OF TAU-MEDIATED MICROTUBULE BUNDLES. Rashmi Gangwar , Peter J. Chung 340-Pos Board B124 IDR-DRIVEN NANOMETER-SCALE RNA HELICASE PROTEIN CLUSTERS (RPCS) ARE DYNAMIC ASSEMBLIES. Him Shweta , Amber Yanas, Masaaki Sobake, Michael C. Owens, Christopher S. Fraser, Kathy F. Liu, Yale E. Board B125 STRUCTURAL DYNAMICS OF THE INTRINSICALLY DISORDERED LINKER REGION OF CARDIAC TROPONIN T. Jasmine Cubuk , Lina Greenberg, Akiva E. Greenberg, Ryan J. Emenecker, Melissa D. Stuchell-Brereton, Alex S. Holehouse, Michael J. Greenberg, Andrea Soranno 342-Pos Board B126 EFFECTS OF PHOSPHORYLATION ON CONFORMATIONAL DYNAMICS OF RNA POLYMERASE II CTD IN VARIANT SEQUENCES. William Barr, Mi chaela Cohen , Kian Sethi, Wei Chen, Scott A. Showalter, K. Aurelia Ball 343-Pos Board B127 DISRUPTING THE HIV-VIF-A3F BINDING SITE THROUGH MUTATION OF STABILIZING RESIDUE. Nina M. van Hoorn , Beilynn Geiss, Elizabeth Miller, Juan Alcantara, K. Aurelia Ball Goldman 341-Pos

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