BPS2025 Full Program

344-Pos Board B128 ALPHA-SYNUCLEIN MONOMER BEHAVIOR UNDER VARYING IONIC STRENGTH AND PH CONDITIONS. Sydney R. Johnson 345-Pos Board B129 A CONSERVED ‘ELECTROSTATIC CASSETTE’ AND AN ALTERNATIVELY SPLICED PROLINE-RICH MOTIF ENABLE COMPACTION AND ISOFORM SPECIFIC AUTOINHIBITION BY THE INTRINSICALLY DISORDERED VARI ABLE DOMAIN OF DYNAMIN-RELATED PROTEIN 1 (DRP1). Anshuman Mohapatra , Rajesh Ramachandran 346-Pos Board B130 PH RESPONSE OF INTRINSICALLY DISORDERED REGIONS. A. M. Whited, Jeffre Allen, Loren Hough 347-Pos Board B131 GENETIC CODE EXPANSION ENABLES STUDIES OF PHOSPHORYLATED TAU FIBRILS. Edward Lien , Cat Hoang Veseley, Richard B. Cooley, Peter Board B132 PROBING THE INFLUENCE OF SEQUENCE ON CYTOTOXIC AND FUNC TIONAL AMYLOID OLIGOMER CONFORMATIONS. Kelsie M. King , Hajar Zaheer, Anne M. Brown 349-Pos Board B133 SELECTIVE BINDING OF LATS1 TO YAP AND KIBRA WW DOMAINS RE VEALED BY NMR AND ITC. Sanjay Ramprasad 350-Pos Board B134 IMPACT OF MEMBRANE PACKING DEFECTS AND CHARGE ON ALPHA SYNUCLEIN BINDING. Orianna Kou , David H. Johnson, John White, Vance Jaeger, Wade F. Zeno 351-Pos Board B135 DISSECTION OF THE CONFORMATIONAL SWITCH THAT REGULATES HUNTINGTIN’S AGGREGATION AND TOXICITY. Piere Rodriguez-Aliaga , Robert P. Sosa, Carlos Bustamante, Judith Frydman 352-Pos Board B136 INVESTIGATING AN ALTERNATIVE MECHANISM TO CALCINEURIN RECRUITMENT THAT ENABLES PKA REGULATION OF NEURONAL L-TYPE CALCIUM CHANNELS. Tvesha Parikh , Kevin C. Crosby, Mark L. Dell’Acqua, Wolfgang Peti, Rebecca Page 353-Pos Board B137 ELECTROCHEMICALLY DRIVEN OPTICAL DYNAMICS OF REFLECTIN PRO TEIN. Yin-Chen Lin , Changxuan Yang, Seren Tochikura, Joshua R. Uzarski, Daniel E. Morse, Lior Sepunaru, Michael J. Gordon 354-Pos Board B138 DE NOVO ENGINEERING OF INTRINSICALLY DISORDERED DESICCATION CHAPERONES. Maciej B. Gielnik , Magnus Kjaergaard 355-Pos Board B139 PHOTO-INDUCED ELECTRON TRANSFER BETWEEN TRYPTOPHAN AND CYSTEINE: SEPARATING PH-DEPENDENCE FROM BUFFER EFFECTS. Crystal F. Ottoway , Lillian Otteson, Gerdenis Kodis, Sara M. Vaiana Condensates: Physical Properties and Modeling I (Boards B140 - B162) 356-Pos Board B140 PREDICTING PHASE SEPARATION PROPENSITY OF PROTEINS. Anisha Shakya , Neha Rana, Rukhillo Kodirov, John King 357-Pos Board B141 MESOSCALE PROPERTIES OF PROTEIN CLUSTERS DETERMINE THE SIZE AND NATURE OF LIQUID-LIQUID PHASE SEPARATION. Gonen Golani , Samuel Safran J. Chung 348-Pos

358-Pos Board B142 REACTIVE OXYGEN SPECIES SOLIDIFY PROTEIN CONDENSATES. Huan Wang , Bruna Favetta, Benjamin S. Schuster, Zheng Shi 359-Pos Board B143 TERNARY PHASE SEPARATION OF POLYAMPHOLYTES AS MODEL INTRIN SICALLY DISORDERED PROTEINS: SEQUENCE SPECIFICITY AND FINITE SIZE EFFECTS. Jonas Wessén, Tanmoy Pal, Suman Das, Hue Sun Chan 360-Pos Board B144 MOLECULAR SIMULATIONS OF THE INTERACTIONS BETWEEN IDP CONDENSATES AND LIPID BILAYERS. Ketsia Zinga , Jeanne C. Stachowiak, Pengyu Ren 361-Pos Board B145 FORMATION OF MICELLES IN IDPS: INSIGHTS FROM MOLECULAR SIMU LATIONS. Rodrigo F. Dillenburg , Lukas S. Stelzl, Edward A. Lemke, Martin Girard 362-Pos Board B146 DISORDERED RNA CONFORMATIONS AND NUCLEOTIDE-SPECIFIC DYNAMICS WITHIN RIBONUCLEOPROTEIN CONDENSATES. Tong Wang , Qingyue Hu, Scout Fronhofer, Lois Pollack 363-Pos Board B147 ELECTROCHEMISTRY AND INHERENT ELECTROCHEMICAL FUNCTIONS OF BIOMOLECULAR CONDENSATES. Xiao Guo, Mina Farag, Wen Yu, Michael Chen, Rohit V. Pappu, Yifan Dai 364-Pos Board B148 TRANSMEMBRANE COUPLING ACCELERATES COARSENING DYNAMICS OF LIQUID-LIKE PROTEIN CONDENSATES. Yohan Lee , Feng Yuan, Jeanne C. Stachowiak 365-Pos Board B149 MULTIPHASE PROTEIN ASSEMBLY OF POSTSYNAPTIC DENSITY IN THREE- AND TWO-DIMENSIONS. Risa Yamada , Giovanni B. Brandani, Shoji Takada 366-Pos Board B150 HIGH PROGRAMMABILITY OF PHYSICAL PROPERTIES OF DNA DROP LETS AND COMPARATIVE ANALYSIS WITH COARSE-GRAINED SIMULA TION. Naoki Yoshida , Kei Goraku, Masahiro Takinoue 367-Pos Board B151 TUNING BIOMOLECULAR LIQUID-LIQUID PHASE SEPARATIONS BY PREF ERENTIAL HYDRATION AND INTERACTION OF SMALL OSMOLYTES WITH PROTEINS. Keiji Kitamura , Ayano Ohshima, Fuka Sasaki, Ryu Yamamoto, Yutaro Shiramasa, Tomoshi Kameda, Soichiro Kitazawa, Ryo Kitahara 368-Pos Board B152 MEASURING RUPTURE FORCES OF INDIVIDUAL CROSSLINKS IN PROTEIN-DNA CONDENSATES. Vikhyaat Ahlawat 369-Pos Board B153 MOLECULAR INSIGHTS INTO PHASE SEPARATION OF POLYHOMEOTIC HOMOLOG USING ATOMISTIC AND COARSE-GRAINED SIMULATIONS: ROLE OF STERILE ALPHA MOTIF DIMERIZATION AND NUCLEIC ACID BINDING. Vithurshan Varenthiraraja , Utkarsh Kapoor 370-Pos Board B154 AN ABERRANT FUSED IN SARCOMA LIQUID DROPLET OF AMYOTROPHIC LATERAL SCLEROSIS PATHOLOGICAL VARIANT, R495X, ACCELERATES LIQUID-SOLID PHASE TRANSITION. Yutaro Shiramasa , Ryu Yamamoto, Norika Kashiwagi, Fuka Sasaki, Sawaka Imai, Mikihito Ike, Soichiro Kitaza wa, Tomoshi Kameda, Ryo Kitahara 371-Pos Board B155 MICROPHASE VERSUS MACROPHASE SEPARATION OFPROTEINS WITH RNA RECOGNITION MOTIFS. Vicky Liu , Min Kyung Shinn, Kiersten Ruff, Rohit V. Pappu

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