BPS2025 Full Program

372-Pos Travel Award Winner INVESTIGATING THE ROLE OF SEQUENCE PATTERNING IN THE MIXING OF POLYMER DENSE PHASES. Lydia L. Good , Tuomas P. Knowles, Robert B. Best 373-Pos Board B157 LIQUID-LIQUID PHASE SEPARATION PROPENSITY OF COILED-COIL PRO TEINS REVEALED BY MOLECULAR SIMULATION. Dominique Ramirez , Loren Hough, Michael R. Shirts 374-Pos Board B158 QUANTIFYING TEMPERATURE-INDUCED CHANGES IN PROTEIN INTER ACTIONS AND PHASE BEHAVIOUR USING HIGH-THROUGHPUT DROPLET MICROFLUIDICS. Charlotte M. Fischer , Hannes Ausserwöger, Tomas Sneideris, Daoyuan Qian, Rob Scrutton, Seema Qamar, Peter St George Hyslop, Tuomas P. Knowles 375-Pos Board B159 Travel Award Winner INVESTIGATING Α-SYNUCLEIN LIQUID CONDENSATES TRANSITION TO AN IRREVERSIBLE AGGREGATED STATE. Irina A. Edu , Aviad Levin, Tomas Sneideris, Charlotte M. Fischer, Tuomas P.J. Knowles 376-Pos Board B160 UNRAVELING THE CONFIRMATIONAL DYNAMICS OF INDIVIDUAL PRO TEINS AND THE BIOPHYSICAL PRINCIPLES UNDERLYING BIOMOLECULAR ASSEMBLIES USING OPTICAL TWEEZERS. Trey Simpson , Nastaran Hadi zadeh Yazdi, Paul Pease, Sheema Rahmanseresht, Andrea Candelli 377-Pos Board B161 CELL-FREE PROTEIN SYNTHESIS AS A PLATFORM FOR STUDYING LIQUID LIQUID PHASE SEPARATION. Natasha Jones , Carolyn E. Mills 378-Pos Board B162 IMMISCIBLE CO-CONDENSATE SYSTEM ON CHROMATIN TO CODE TRAN SCRIPTIONAL STATES. Kibeom Hong , Bo Huang Ribosomes and Translation (Boards B163 - B183) 379-Pos Board B163 Travel Award Winner MAGNESIUM ION ASSIGNMENT AND ROLE IN RIBOSOME SUBUNIT ROTATION. George Wanes , Paul C. Whitford 380-Pos Board B164 MODULATION OF RIBOSOMAL FRAMESHIFTING THROUGH INTERAC TIONS BETWEEN RIBOSOMES. Jin-Der Wen 381-Pos Board B165 EXPLORING PROTEIN STRUCTURE AND DYNAMICS AT BIRTH IN THE PRESENCE OF MOLECULAR CHAPERONES. Neomi Millan , Hongqing Guan, Zhemin Zhang, Edward W. Yu, Silvia Cavagnero 382-Pos Board B166 DEVELOPING A METHOD FOR SCREENING INHIBITORS OF RFC-DEPEN DENT TERMINATION OF PROTEIN SYNTHESIS AT PTCS. Adam A. Jabak , Hong Li, Saleem Y. Bhat, Yale E. Goldman, Barry S. Cooperman 383-Pos Board B167 CHARACTERIZING THE IMPACT OF IONS ON P/E HYBRID FORMA TION. Stephen A. Whitcomb , Sandra Byju, George Wanes, Paul C. Board B168 COUPLING AMONG REACTION STEPS IN TERMINATION OF EUKARYOTIC PEPTIDE SYNTHESIS. Arpan Bhattacharya , Saleem Y. Bhat, Hong Li, John D. Lueck, Barry S. Cooperman, Yale E. Goldman 385-Pos Board B169 Travel Award Winner POXVIRUS MODIFICATION OF HOST RIBOSOMES CONFERS A SELECTIVE TRANSLATIONAL ADVANTAGE TO VIRAL MRNA. Aaron Ferrell , Derek Walsh, Peter Shen Board B156 Whitford 384-Pos

386-Pos Board B170 REGULATORY MECHANISMS IN THE SRP TARGETING PATHWAY. Ruilin Qian 387-Pos Board B171 MUON APPROACH FOR RIBOSOME SIMULATIONS: ILLUSTRATION OF DEACYL-TRNA RELEASE FROM E SITE. Jigneshkumar D. Prajapati , Karissa Y. Sanbonmatsu 388-Pos Board B172 DIRECT OBSERVATION OF TMRNA-MEDIATED NON-STOP RIBOSOME RECOGNITION AND RESCUE. Qiongfang S. Zhang , Riley C. Gentry, Ruben L. Gonzalez 389-Pos Board B173 REST ASSURED: PROGRAMMED TRANSLATIONAL STALLING STUDIED BY MEANS OF MD SIMULATIONS. Sara Gabrielli , Lars V. Bock 390-Pos Board B174 HUMAN AMINOACYL-TRNA PIVOTS DURING ACCOMMODATION. Karissa Y. Sanbonmatsu, Dylan Girodat 391-Pos Board B175 Travel Award Winner ASSEMBLY OF THE BACTERIAL RIBOSOME WITH CIRCULARLY PERMUTED 23S RNA. Xiyu Dong , Kai Sheng, Luca F.R. Gebert, Sriram Aiyer, Ian J. MacRae, Dmitry Lyumkis, James R. Williamson 392-Pos Board B176 3D SINGLE-MOLECULE TRACKING TO STUDY KINETICS OF PROTEIN TAR GETING IN LIVING BACTERIA. Ivan L. Volkov , Erik Lundin, Reut Orange Kedem, Mikhail Metelev, Yoav Shechtman, Magnus Johansson 393-Pos Board B177 Travel Award Winner DIAMOND-BLACKFAN ANEMIA ASSOCIATED-MUTATIONS PERTURB UL5 HELIX STABILITY AND CONFORMATIONAL ENSEMBLE. Anuradha Rai Chowdhury , Divya Sapkota, Dylan Girodat 394-Pos Board B178 COMPUTATIONAL MODELING OF MAGNESIUM ION SOLVATION AROUND ESCHERICHIA COLI 70S RIBOSOME USING 3D REFERENCE INTERACTION SITE MODEL OF MOLECULAR SOLVATION. Tiannah York Van Elslande , Felipe Silva Carvalho, David Case, Silvia Cavagnero, Tyler Luchko 395-Pos Board B179 INTEGRATIVE HIGH-THROUGHPUT SCREENING AND MOLECULAR SIMU LATIONS REVEALS HOW VIRAL SEQUENCE MOTIFS REGULATE MRNA STABILITY. Matthew C. Chan , Phillip Burke, Heungwon Park, Melody Campbell, Arvind R. Subramaniam 396-Pos Board B180 MULTITASKING AT THE RIBOSOME: HOW DOES NAC SENSE DIFFERENT NASCENT PROTEINS? Radoslaw J. Gora 397-Pos Board B181 STRUCTURAL DYNAMICS OF RIBOSOME-STALLING PEPTIDES IN THE RIBOSOMAL EXIT TUNNEL UNCOVERED BY MD SIMULATIONS. Ole Berendes , Sara Gabrielli, Helmut Grubmüller, Lars V. Bock 398-Pos Board B182 Β-AMINO ACIDS REDUCE TERNARY COMPLEX STABILITY AND ALTER THE TRANSLATION ELONGATION MECHANISM. Francisco Aaron Cruz Navarrete , Wezley Griffin, Yuk-Cheung Chan, Maxwell Martin, Jose L. Alejo Amaya, Ryan A. Brady, Kundhavai Natchiar, Isaac J. Knudson, Roger B. Altman, Alanna Schepartz, Scott J. Miller, Scott C. Blanchard 399-Pos Board B183 ADVANCED IMAGING OF RIBOSOMAL ASSEMBLY AND RRNA OPERON ORGANIZATION IN E COLI VIA MINFLUX. Sijin Chen , Kai Sheng, Susanna Ekholm-Reed, James R. Williamson

F R I D A Y

S U N D A Y

35