BPS2025 Full Program

Protein-Nucleic Acid Interactions I (Boards B184 - B218)

413-Pos Board B197 INVESTIGATIONS OF THE MACROMOLECULAR INTERACTIONS BETWEEN HUMAN RAD51 AND SSDNA/DSDNA JUNCTIONS. Grace Young , Mark Board B198 SINGLE STRANDED DNA TRANSLOCATION AND DNA HELICASE ACTIVI TIES OF MYCOBACTERIUM TUBERCULOSIS UVRD1 DIMERS. Kacey N. Mersch , Binh Nguyen, Ankita Chadda, Eric Tomko, Eric A. Galburt, Timothy M. Lohman 415-Pos Board B199 LINKING MDS/AML PATIENT DISEASE PHENOTYPES WITH DDX41 BIOCHEMISTRY USING HIGH-THROUGHPUT MICROFLUIDICS ENZYME KINETICS (HT-MEK). Cheng Ern Yap , Hunter Krzysik, Aaron A. Hoskins 416-Pos Board B200 CONSTRUCTING PROTEIN TARGET SEARCH DIFFUSION-ASSOCIATION FREE ENERGY LANDSCAPE AROUND DNA BINDING SITES AND LINK LOCAL MOLECULAR DYNAMICS WITH GENOME-WIDE PROFILING. Biao Wan, Carmen Al Masri, Jin Yu 417-Pos Board B201 INVESTIGATION OF MIR-145-5P AND FMRP BINDING TO THE 3’-UTR OCT4 MRNA G-QUADRUPLEX FORMING SEQUENCE. Manju Kasaju , Mihaela-Rita Mihailescu 418-Pos Board B202 MECHANICS OF THE BACTERIAL INTEGRON SYNAPTIC COMPLEX DIC TATES THE RECOMBINATION EFFICIENCY DURING ADAPTATION. Ekat erina Vorobevskaia, Céline Loot, Didier Mazel, Michael Schlierf 419-Pos Board B203 CHARACTERIZING KINETICS OF TRANSLOCATION AND FREE ENERGIES OF NUCLEOTIDE INSERTION IN THE HUMAN MITOCHONDRIAL RNA POLYMERASE VIA ALL-ATOM MOLECULAR DYNAMICS. Shannon J. McElhenney , Jin Yu 420-Pos Board B204 CHARACTERIZING EZRIN RNA BINDING. Prakriti Tiwari , Emre Deniz, Akyut Üren 421-Pos Board B205 SINGLE MOLECULE FORSTER RESONANCE ENERGY TRANSFER (SMFRET) REVEALS MULTIPLE DNA CONFORMATIONS IN GEN-5’FLAP COMPLEX ES. Shunsen Ren 422-Pos Board B206 SEQUENCE-DEPENDENT CO-CONDENSATION OF LSR2 WITH DNA ELUCI DATES THE MECHANISM OF GENOME COMPACTION IN MYCOBACTERI UM TUBERCULOSIS . Prakshi Gaur , Thejas Satheesh, Rohit Singh, Sneha Shahu, Saminathan Ramakrishnan, Mansi Srivastava, Shreyasi Neogi, Sandeep Choubey, Mahipal Ganji 423-Pos Board B207 COMPUTATIONAL INSIGHTS INTO THE ROLE OF HELICAL DIPOLES IN PROTEIN-DNA INTERACTIONS. Feng Yu , Susan E. Tsutakawa 424-Pos Board B208 SINGLE MOLECULE KINETIC FINGERPRINTING REVEALS A UNIFYING MODEL OF MIRNA GUIDED MRNA SILENCING. Tanmay Chatterjee , Shankar Mandal, Sujay Ray, Alexander Johnson-Buck, Nils G. Walter 425-Pos Board B209 REPARAMETERIZATION OF DNA-PROTEIN INTERACTION IMPROVES THE DESCRIPTION OF NANOPORE DNA SEQUENCING. Jingqian Liu , Crystal Rodriguez, Min Chen, Aleksei Aksimentiev Hedglin 414-Pos

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400-Pos Board B184 COMBINED CRISPR-ACTIVATION AND CRISPR-INTERFERENCE CAPABILI TIES USING DCAS9 AND G-QUADRUPLEX STRUCTURES. Hamza Balci , Mohammad L. Kabir, Sineth G. Kodikara, Soumitra Basu, Janan Alfehaid 401-Pos Board B185 HYPERACYLATION FROM CELLULAR METABOLITES DESTABILIZES AND UNWINDS NUCLEOSOMES. Micah J. McCauley , Joha Joshi, Michael Morse, Nicole A. Becker, Matthew Amato, John Smestad, Ioulia F. Rouzina, L. James Maher, Mark C. Williams 402-Pos Board B186 INVESTIGATING THE MOLECULAR MECHANISMS OF GAIN OF FUNCTION MUTATIONS IN Λ PHAGE TRANSCRIPTION FACTOR CRO VIA MOLECULAR DYNAMICS SIMULATIONS. Ryan F. Hebert , Alexander Perez, Jeffery M. Wereszczynski 403-Pos Board B187 DNA HYDROGELS AND THEIR APPLICATIONS. David C. Brown 404-Pos Board B188 MINING ANTIBODY-ANTIGEN CO-CRYSTALS FOR KNOB-SOCKET MOTIFS THAT DETERMINE SPECIFICITY AND AFFINITY. Kalee Thao , Margit Klemer De Lasse, Tiffanie Jiang, Hyun Joo, Jerry Tsai 405-Pos Board B189 A FUNCTIONAL CROSS-LINKED E. COLI UVRD HELICASE DIMER. Binh Nguyen , Ankita Chadda, Eric A. Galburt, Timothy M. Lohman 406-Pos Board B190 STUDYING DNA TARGET SEARCH: SINGLE MOLECULE EXPERIMENTS AND SIMULATIONS. Katie Polanco , Harold Sartiah, Mateo Price-Otero, Allen C. Price 407-Pos Board B191 TESTIS-SPECIFIC HISTONE VARIANT H2BW2 CAUSES NUCLEOSOME DESTABILIZATION AND ASYMMETRIC DNA UNWRAPPING. Xinpeng Bai , Thi Thuy Nguyen, Dongbo Ding, Matthew Yu Hin Pang, Yue Liu, Tingyu Jin, Toyotaka Ishibashi 408-Pos Board B192 VISUALIZING AND MANIPULATING PROTEIN-RNA INTERACTIONS AT THE SINGLE MOLECULE LEVEL. Paul Pease 409-Pos Board B193 SARS-COV-2 NUCLEOCAPSID PROTEIN NONSPECIFICALLY INTERACTS WITH AND FOLDS DSDNA. Jonathan Xing , Ashley Carter 410-Pos Board B194 SINGLE-MOLECULE LEVEL ANALYSIS OF ADAR1 BINDING AND A-TO-I EDITING ON DOUBLE-STRANDED RNA. Sunghyun Cho , Xiangyu Deng, Yang Gao, Sua Myong 411-Pos Board B195 TAU CONDENSATION ON DNA AND LOCALIZATION ON CENTROMERES: A POTENTIAL LINK TO CELL DIVISION. Celine Park , Jaehun Jung, Yuri Hong, Chaelin Lee-Eom, Sang-Hyun Rah, Keunsang Yang, Jaehyeon Shin, Ayoung Jeong, Seokyun Hong, Jong-Bong Lee, Dong Soo Hwang, Min Ju Shon 412-Pos Board B196 USE OF NUCLEAR EXTRACTS TO STUDY COHESIN IN OPTICAL TWEEZERS COMBINED WITH FLUORESCENCE MICROSCOPY. Bartosz Malinski , Col leen Caldwell, Marco Simonetta, Gijs J. Wuite

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