Biophysical Society 66th Annual Meeting Program Guide

Opening New Vistas in Biophysical Discovery

Program

The Biophysical Society is grateful to its Industry Partners.

GOLD

PLATINUM

SILVER

Learn more about becoming a Biophysical Society Industry Partner at www.biophysics.org.

Biophysics Week is an opportunity to promote, educate, celebrate, and engage others in biophysics research. GET INVOLVED! Plan to participate in BPS sponsored events as well as virtual or local Affiliate Events. You can also host your own Biophysics Week Affiliate Event. Register your event to receive advertising support from BPS. GEAR UP! This year’s Biophysics Week t-shirt is now available. Pre-order your shirt before they sell out! SUPPORT BIOPHYSICS WEEK! Help promote Biophysics Week to your peers, colleagues, and friends. Use the resources available on the website to share information and get the word out. #BiophysicsWeek Get ready to celebrate biophysics and the important work that biophysicists do!

Visit biophysics.org/ BiophysicsWeek for more information.

The Biophysicist aims to highlight and nurture education, and its scholarship and devel- opment. The journal serves a worldwide audience to make fundamental concepts and techniques in biophysics (and related disciplines), as well as evidence-based pedagogical practice, accessible to individuals at all levels: undergraduate, graduate and post-graduate students/trainees, active researchers, and scholars of biophysics teaching and learning. Why publish in The Biophysicist

• The only journal to publish research on teaching biophysics • Open access • Accepts Reports as well as Research Articles • Offers a Student Forum • Editors who go beyond evaluation to mentor authors • Low publication costs

Explore what the journal can offer you at thebiophysicist.org

GUIDE TO THE ANNUAL MEETING

About the BPS Annual Meeting The Biophysical Society (BPS) Annual Meeting is the largest gathering of biophysicists in the world. With over 200 sessions and more than 3,000 poster presentations, it can be overwhelming! Use this guide to help you get the most from your attendance at this world famous event.

Scientific Sessions The BPS Annual Meeting is known for its many types of sessions, often taking place concurrently. Each type has its own distinct scope, format, and speaker makeup. Symposia

Professional Development The Annual Meeting includes daily sessions and resources for the professional development of biophysicists at all stages of their careers: undergrads and grad students, early and mid-stage, and senior scientists. These sessions are held before, after, and in-between the scientific sessions.

Workshops • Technique-oriented sessions • Four-to-eight speakers per two-hour session • Two-to-four held concurrently on Tuesday evenings Subgroup Programs • Scientific sessions held Saturday • Feature speakers presenting the latest research in biophysics subfields Biophysical Society Lecture • One-hour presentation by a world-renowned biophysicist

• Broad topics featuring talks by leading researchers presenting new research • Four speakers per two-hour session • Two-to-three held concurrently Platforms • More focused topics selected from among submitted abstracts held concurrently with symposia • Eight speakers per two-hour session, including early career and student researchers • Approximately six held concurrently during each symposium session

Career Development Center Open all day, includes job and resume postings, interview scheduling, CV reviews, and job-related workshops Breakfasts For students and postdocs to network and learn about available resources Panel Discussions Expert presentations on career options, guidance on career transitions, funding resources, science policy Opening Reception • Hors d’oeuvres and cash bar First-Time Attendee Drop-By • Information on how to navigate the Meeting Dinner Meet-Ups • Local student and early career attendees available Sunday - Tuesday at 6 pm at the Society Booth to help you explore local restaurants and neighborhoods

Workshops On networking, public speaking, teach- ing and science education, careers in industry and academia, and optimizing graduate and postdoc experiences Exhibits Over 120 displays of new equipment,

publications, and products Exhibitor Presentations

Hands-on demonstrations conducted by exhibiting companies of scientific products and their uses

Posters Most interactive and well-attended scientific sessions of the meeting. Poster Presenters

Social and Networking Events

New Member Welcome • Opportunity to meet and socialize with newmembers and members of Society governance and committees

Board Assignments Board numbers (B1, B2, B3, LB1, LB2, etc.) indicate the location of the poster board in the Exhibit Hall. Poster numbers (250-Pos, 251-Pos, etc.) correspond with the number assigned to each poster in the online Abstracts Issue.

It is important to present science, but also have posters available for attendee viewing prior to and following presentations. Poster Schedule Please refer to the programming notice, desktop planner, or mobile app for the date and time of poster presentations.

Presentation Date

Sunday, February 20

Monday, February 21

Tuesday, February 22 Monday after 6 pm Tuesday before 4 pm

Wednesday, February 23 Wednesday after 7 am Wednesday before 3 pm

Setup Time

Saturday after 6 pm

Sunday after 6 pm

Removal Time

Sunday before 5:30 pm

Monday before 5:30 pm

PLEASE NOTE: POSTERSWILL NOT BE COLLECTED OR STORED FOR PICK UP AT A LATER TIME. The e-Poster Gallery will be available for viewing in the mobile app and desktop planner during the meeting and will be available on-demand March 14 - April 30. If you are presenting a poster check for comments and emails.

Visit booth 804 to see live measurements

DriveAFM Performance without compromise Come to booth #804 and experience AFM beyond tapping mode with CleanDrive

Major andminor grooves of dsDNA. 50 nmscan.

Isolated capsids of Herpes Simplex virus. 350 nm scan.

Atomic lattice of HOPG. 4 nmscan.

66th Biophysical Society Annual Meeting February 19–23, 2022 • San Francisco, California, USA

Table of Contents

Code of Conduct . . . . . . . . . . . . . . . . . . . . III Moscone Center Facilities Maps. . . . . . . . . . . . . . . . . . . . . IV Society Governance . . . . . . . . . . . . . . . . . . VIII General Information . . . . . . . . . . . . . . . . . . . X Society Committee Meetings Schedule . . . . . . . . . . XIII Professional Development & Education Sessions . . . . . . XIV Travel Awards . . . . . . . . . . . . . . . . . . . . XVI Ancillary Meetings . . . . . . . . . . . . . . . . . . XXIV Friday Schedule of Events . . . . . . . . . . . . . . . . 1 Satellite Meeting . . . . . . . . . . . . . . . . . . . . 2 Saturday Schedule of Events . . . . . . . . . . . . . . . 3 Subgroup Dinner Schedule . . . . . . . . . . . . . . . . 3 Subgroup Meetings . . . . . . . . . . . . . . . . . . . 3 Bioengineering . . . . . . . . . . . . . . . . . . . . 4 Biological Fluorescence . . . . . . . . . . . . . . . . . 4 Intrinsically Disordered Proteins . . . . . . . . . . . . . 4 Macromolecular Machines and Assemblies . . . . . . . . 5 Membrane Structure and Function . . . . . . . . . . . . 5 Membrane Transport . . . . . . . . . . . . . . . . . 5 Motility and Cytoskeleton . . . . . . . . . . . . . . . 6 Single-Molecule Forces, Manipulation, and Visualization . . . 6 Mechanobiology . . . . . . . . . . . . . . . . . . . 6 Bioenergetics, Mitochondria & Metabolism . . . . . . . . 6 Biopolymers in Vivo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Channels, Receptors, and Transporters . . . . . . . . . . 7 Membrane Fusion, Fission, and Traffic . . . . . . . . . . 7 Multicale Genome Organization . . . . . . . . . . . . . 8 Nanoscale Approaches to Biology . . . . . . . . . . . . 8 Physical Cell Biology . . . . . . . . . . . . . . . . . . 8 Theory and Computation . . . . . . . . . . . . . . . . 9 Cryo-EM . . . . . . . . . . . . . . . . . . . . . . . 9 Sunday Schedule of Events . . . . . . . . . . . . . . . 11 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . 14 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . 14 Symposia 10:45 am –12:45 pm . . . . . . . . . . . . . . 18 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . 18 Symposia 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 22

Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 23 SRAA Competition 6:00 pm –9:00 pm . . . . . . . . . . . 26 (see page 48 for a list of SRAA Participants) Sunday Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Monday Schedule of Events . . . . . . . . . . . . . . . 54 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . 57 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . 57 Symposia 10:45 am –12:45 pm . . . . . . . . . . . . . . 60 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . 60 Symposia 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 66 Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 66 Awards & 2022 Biophysical Society Lecture . . . . . . . . . 69 Monday Posters . . . . . . . . . . . . . . . . . . . . 70 Tuesday Schedule of Events . . . . . . . . . . . . . . . 91 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . 94 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . 94 Symposium 10:45 am –12:45 pm . . . . . . . . . . . . . 97 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . 98 Symposia 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 101 Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . 102 Workshops 7:30 pm –9:30 pm . . . . . . . . . . . . . . 104 Tuesday Posters . . . . . . . . . . . . . . . . . . . . 105 Wednesday Schedule of Events . . . . . . . . . . . . . 127 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . 129 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . 129 Symposia 1:00 pm –3:00 pm . . . . . . . . . . . . . . . 131 Platforms 1:00 pm –3:00 pm . . . . . . . . . . . . . . . 132 Wednesday Posters . . . . . . . . . . . . . . . . . . 134 Exhibits . . . . . . . . . . . . . . . . . . . . . . . 154 Exhibitor Presentations . . . . . . . . . . . . . . . . . 155 Exhibitor List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 Product Categories . . . . . . . . . . . . . . . . . . 176 Author Index . . . . . . . . . . . . . . . . . . . . . 181

2022 Biophysical Society Lecturer

About the Image The 2022 image featured on the cover is the catalytic repertoire of heme proteins covers an astonishing range of reactions, yet we have only explored a tiny fraction of the POSSIBLE chemistry of life.

Frances Arnold California Institute of Technology, USA

Innovation by Evolution: Bringing New Chemistry to Life

List of Advertisers in the 2022 Annual Meeting Program

Nanion Technologies Nanosurf

The Biophysical Society would like to thank the following companies for their generous support of the Annual Meeting:

Axiom Optics Beckman Coulter Life Sciences Bruker Carl Zeiss Microscopy LLC Cell Press Chroma Technology Curi Bio Delmic Dynamic Biosensors Elements srl Fluidic Analytics Fluxion Biosciences GenNext Technologies

HarvardBioscience Interherence GmbH IOP Publishing

ISS Inc JASCO Journal of General Physiology (JGP) LEICA MICROSYSTEMS INC LUMICKS Mad City Labs Inc

Malvern Panalytical Nanion Technologies Nicoya Nikon Instruments Physics Today Sophion Bioscience A/S Sutter Instrument

As of January 4, 2022

II

Biophysical Society Code of Conduct, Anti-Harassment Policy

The Biophysical Society (BPS) is committed to providing an environment that encourages the free expression and exchange of scientific ideas. As a global, professional Society, the BPS is committed to the philosophy of equal opportunity and respectful treatment for all, regardless of national or ethnic origin, religion or religious belief, gender, gender identity or expression, race, color, age, marital status, sexual orientation, disabilities, veteran status, or any other reason not related to scientific merit. All BPS meetings and BPS-sponsored activities promote an environment that is free of inappropriate behavior and harassment by or toward all attendees and participants of Society events, including speakers, organizers, students, guests, media, exhibitors, staff, vendors, and other suppliers. BPS expects anyone associated with an official BPS-sponsored event to respect the rules and policies of the Society, the venue, the hotels, and the city. Definition of Harassment The term “harassment” includes but is not limited to epithets, unwelcome slurs, jokes, or verbal, graphic or physical conduct relating to an individual’s race, color, religious creed, sex, national origin, ancestry, citizenship status, age, gender or sexual orientation that denigrate or show hostility or aversion toward an individual or group. Sexual harassment refers to unwelcome sexual advances, requests for sexual favors, and other verbal or physical conduct of a sexual nature. Behavior and language that are welcome/acceptable to one person may be unwelcome/ offensive to another. Consequently, individuals must use discretion to ensure that their words and actions communicate respect for others. This is especially important for those in positions of authority since individuals with lower rank or status may be reluctant to express their objections or discomfort regarding unwelcome behavior. It does not refer to occasional compliments of a socially acceptable nature. It refers to behavior that is not welcome, is personally offen- sive, debilitates morale, and therefore, interferes with work effectiveness. The following are examples of behavior that, when unwelcome, may constitute sexual harassment: sexual flirtations, advances, or propositions; verbal comments or physical actions of a sexual nature; sexually degrading words used to describe an individual; a display of sexually suggestive objects or pictures; sexually explicit jokes; unnecessary touching. Attendees or participants who are asked to stop engaging in harassing behavior are expected to comply immediately. Anyone who feels harassed is encouraged to immediately inform the alleged harasser that the behavior is unwelcome. In many instances, the person is unaware that their conduct is offensive and when so advised can easily and willingly correct the conduct so that it does not reoccur. Anyone who feels harassed is NOT REQUIRED to address the person believed guilty of inappropriate treatment. If the informal discussion with the alleged harasser is unsuccessful in remedying the problem or if the complainant does not feel comfortable with such an approach, they can report the behavior as detailed below. Reported or suspected occurrences of harassment will be promptly and thoroughly investigated. Following an investigation, BPS will immediately take any necessary and appropriate action. BPS will not permit or condone any acts of retaliation against anyone who files harassment complaints or cooperates in the investigation of same.

Reporting a Violation Violations of this Conduct Policy should be reported immediately. If you feel physically unsafe or believe a crime has been committed, you should report it to the police immediately. To report a violation to BPS: • You may do so in person at the Annual Meeting at the BPS Business Office in the convention center. • You may do so in person to BPS senior staff at Thematic Meetings, BPS Conferences, or other BPS events. • At any time (during or after an event), you can make a report through http://biophysics.ethicspoint.com or via a dedicated hotline (phone numbers listed on the website) which will collect and relay information in a secure and sensitive manner. Reported or suspected occurrences of harassment will be promptly and thoroughly investigated per the procedure detailed below. Following an investigation, BPS will immediately take any necessary and appropriate action. BPS will not permit or condone any acts of retaliation against anyone who files harassment complaints or cooperates in the investigation of same. Investigative Procedure All reports of harassment or sexual harassment will be treated seriously. However, absolute confidentiality cannot be promised nor can it be assured. BPS will conduct an investigation of any complaint of harassment or sexual harassment, which may require limited disclosure of pertinent information to certain parties, including the alleged harasser. Once a complaint of harassment or sexual harassment is received, BPS will begin a prompt and thorough investigation. Please note, if a complaint is filed anonymously, BPS may be severely limited in our ability to follow-up on the allegation. • An impartial investigative committee, consisting of the current President, President-Elect, and Executive Officer will be established. If any of these individuals were to be named in an allegation, they would be excluded from the committee. • The committee will interview the complainant and review the written complaint. If no written complaint exists, one will be requested. • The committee will speak to the alleged offender and present the complaint. • The alleged offender will be given the opportunity to address the complaint, with sufficient time to respond to the evidence and bring his/her own evidence. • If the facts are in dispute, the investigative team may need to interview anyone named as witnesses. • The investigative committee may seek BPS Counsel’s advice. • Once the investigation is complete, the committee will report their findings and make recommendations to the Society Officers. • If the severity of the allegation is high, is a possible repeat offense, or is determined to be beyond BPS’s capacity to assess claims and views on either side, BPS may refer the case to the alleged offender’s home institution (Office of Research Integrity of similar), employer, licensing board, or law enforcement for their investigation and decision. Disciplinary Actions Individuals engaging in behavior prohibited by this policy as well as those making allegations of harassment in bad faith will be subject to disciplinary action. Such actions range from a written warning to ejection from the meeting or activity in question without refund of registration fees, being banned from participating in future Society meetings or Society-sponsored activities, being expelled from membership in the Society, and reporting the behavior to their employer or calling the authorities. In the event that the individual is dissatisfied with the results of the investigation, they may appeal to the President of the Society. Any questions regarding this policy should be directed to the BPS Executive Officer or other Society Officer.

III

Moscone Center

Exhibition Level

Room 24/25 BPS 2022 Lecture

• Poster Pickup • First Time Attendee Drop By • Undergraduate Poster Award Competition • Opening Mixer • JUST-B Poster Session • Speed Networking

HALL C

HALL B

HALL A

Exhibit Hall ABC

Gender Inclusive Restrooms

• Posters & Exhibits • Education and Career Opportunities Fair • SRAA Competition

• Exhibitor Lounge • Image Contest • Travel Awardee Reception

IV

Moscone Center

Upper Mezzanine, Lobby Level, Lower Mezzanine

Gender Inclusive Restrooms

Career Development Workshop Room

Career Development Center

UPPER MEZZANINE

Room 153, 154, 155, 156 Meeting Rooms

NORTH LOBBY

Exhibitor Presentations

Exhibitor Presentations

• Society Booth • Publications Booth

• Registration • Help Desk

Society Office

Speaker Ready Room

Family Room

SOUTH LOBBY

56 54 Gender Inclusive Restrooms 52

Undergraduate Student Lounge

Meditation Room

60

50

62

76 74 72 70 58

LOWER MEZZANINE

V

Moscone Center

Level 2

MISSION STREET

FOURTH STREET

THIRD STREET

HOWARD STREET

Meeting Rooms

TERRACE

201

202 203 204 205 206 207

208

SAN FRANCISCO BALLROOM

209 210 211 212 213 214 215

216

TERRACE

Gender Inclusive Restrooms

FOLSOM STREET

Meeting Rooms

VI

Moscone Center

Level 3

MISSION STREET

FOURTH STREET

THIRD STREET

HOWARD STREET Meeting Rooms

Meeting Rooms

TERRACE

Gender Inclusive Restrooms

305

306 307 308

301

302 303

304

309 310

312 313 314

311

TERRACE

FOLSOM STREET

Meeting Rooms

Meeting Rooms

VII

Biophysical Society

Biophysical Society

2022 Program Committee

Jennifer Ross , Syracuse University Baron Chanda , Washington University, 2023 Program Co-Chair Janice Robertson , Washington University, 2023 Program Co-Chair Patricia Bassereau , Institut Curie, 2021 Program Co-Chair Bertrand Garcia-Moreno , Johns Hopkins University, 2021 Program Co-Chair

Elizabeth Komives , University of California, San Diego, Co-Chair Arthur G. Palmer, III , Columbia University, Co-Chair Michelle Digman , University of California, Irvine Teresa Giraldez , Universidad de La Laguna Anna Moroni , University of Milan

BPS Officers Frances Separovic , President Gail Robertson , President-Elect Catherine A. Royer , Past President Samantha Harris , Treasurer Erin Sheets , Secretary

Society Office Staff

Jennifer L. Pesanelli , Executive Officer Dorothy Chaconas , Director of Meetings & Exhibits Catie Curry , Publications Coordinator Darren Early , Managing Editor Leann Fox , Director of Advocacy and Public Affairs Jennifer Fraser , Meetings Coordinator Ally Levine , Sales & Exhibits Manager John Long , Director of Publications Laura Phelan , Communications & Content Manager Margaret Mainguy , Programs Coordinator

BPS Council Term Ending 2022 Michelle A. Digman Marta Filizola Joseph A. Mindell Anna Moroni Term Ending 2023 Erin C. Dueber Gilad Haran Francesca M. Marassi Carolyn A. Moores Term Ending 2024 Henry Colecraft Kumiko Hayashi Susan Marqusee Kandice Tanner

Harris Povich , Director of Finance & Operations Saran Ramu , Director of Information Technology Caitlin Simpson , Membership Manager Jesse S. Vaquez Thielen , Peer Review Coordinator Elizabeth Vuong , Director of Marketing, Communications & Outreach Stacey Wendelbo , Programs Manager Ray Wolfe , Creative Director & IT Systems Engineer Umi Zhou , Meetings Manager

Sorting and Programming of 2022 Abstracts Sorting and programming of the 2022 Annual Meeting abstracts into poster and platform sessions was completed by: Patricia Bassereau, Baron Chanda, Henry Colecraft, Erin Dueber, Marta Filizola, Teresa Giraldez, Ruben Gonzalez, Gilad Haran, Samantha Harris, Kumiko Hayashi, Syma Khalid, William Kobertz, Elizabeth Komives, Francesca Marassi, Susan Marqusee, Joseph Mindell, Carolyn Moores, Anna Moroni, Arthur G. Palmer, III, David Piston, Janice Robertson, Jennifer Ross, Catherine Royer, James Sellers, Frances Separovic, and Erin Sheets.

VIII

Biophysical Society

Biophysical Society

Biophysical Journal Vasanthi Jayaraman, Editor-in-Chief Heiko Heerklotz , Associate Editor Sudha Chakrapani, Associate Editor Jason Kahn , Associate Editor Anne Kenworthy , Associate Editor Alex Mogilner , Associate Editor David Sept , Associate Editor Elizabeth Rhoades , Associate Editor Meyer Jackson , Associate Editor

The Biophysicist Samuel Safran , Editor-in-Chief Gundula Bosch , Editor Andrew Feig , Editor Wolfgang Losert , Editor Phil Nelson , Editor Les Satin , Editor Patricia Soto , Editor

Biophysical Reports Jörg Enderlein , Editor-in-Chief Shi-Wei Chu , Associate Editor

Yuval Ebenstein , Associate Editor Ulrike Endesfelder , Associate Editor Hagen Hofmann , Associate Editor Andrey Klymchenko , Associate Editor Dmitrii E. Makarov , Associate Editor Aleksandra Radenovic , Associate Editor Alexandra Ros , Associate Editor Paul Schanda , Associate Editor Erdinc Sezgin , Associate Editor Yoav Schectman , Associate Editor Kandice Tanner , Associate Editor Sharon Grayer Wolf , Associate Editor

Mark Your Calendars! Future BPS Annual Meetings

69 th Annual Meeting February 15–19, 2025 Los Angeles, California 70 th Annual Meeting February 21–25, 2026 San Francisco, California

67 th Annual Meeting February 18–22, 2023 San Diego, California 68 th Annual Meeting February 10–14, 2024 Philadelphia, Pennsylvania

IX

General Information All functions will be held in the Moscone Center , unless otherwise noted.

Badges Badges are required for admission to all scientific sessions, including Friday Drug Discovery Satellite Meeting, Saturday subgroup symposia, poster areas, exhibits, and social functions. Guest registration is only for admittance to the Opening Mixer on Saturday night and Reception on Monday night. It does not include admission to scientific sessions, post- ers, or exhibits. All attendees and guests MUST be registered no later than February 7, 2022, in order to have vaccination verification. There is a $30 fee to reprint a lost or forgotten badge. Badge Pick-Up, South Lobby Friday 3:00 pm –5:00 pm Saturday 7:30 am –6:30 pm Sunday–Tuesday 7:30 am –5:00 pm Wednesday 8:00 am –3:00 pm Banking and Currency Exchange Bank transactions can be done during regular bank business hours at Bank of America, 1 Powell Street, CA 94102. Please bring two forms of identification with you. Monday Holiday Closed Tuesday–Thursday 9:00 am –5:00 pm Friday 9:00 am –6:00 pm Saturday 10:00 am –2:00 pm Sunday Closed Foreign Currency Exchange Foreign Currency Exchange and travelers’ insurance services may be available at booths and automated currency exchanges machines located throughout the San Francisco Airport International Terminal’s pre- and post-security areas or at Terminal 3, at post-security, Boarding Area F, near gate 71. Business Center, Moscone The business center located in the Moscone Center will remain closed throughout the meeting. Should you have shipping needs please see Freeman at the Freeman Desk located in the Exhibit Hall. Should you need copying services, there is a FedEx located in the Marriott Marquis or you can check with your hotel. Career Development Center, Esplanade, Room 152 Services are available for both those seeking a position and employers with positions to fill. Please note, the Career Development Center is the only place to post job openings. Unauthorized notices placed elsewhere in the Moscone Center will be removed. Saturday 12:00 noon –7:00 pm Sunday 8:00 am –6:30 pm Monday–Tuesday 8:00 am –5:30 pm Certificates of Attendance Certificates of Attendance may be obtained in person in the Society Meeting Office, in the South Lobby, Room 105, or at the Society Help Desk located at registration in the South Lobby.

Code of Conduct The Biophysical Society Annual Meeting provides an environment that encourages free and respectful expression and exchange of scientific ideas. Please review the Code of Conduct policy (page III) that all meet- ing participants must follow. Coat Check/Luggage Storage, South Lobby The cost is $3.00 per checked coat or small handbag and $5.00 per checked luggage. Please do not bring luggage to meeting rooms. If you are planning to check items, plan to arrive early to ensure that you are not late for sessions due to long lines. Dinner Meet-Ups Interested in making new acquaintances and experiencing the cuisine of San Francisco? Meet at the Society Booth each evening, Sunday through Tuesday, at 6:00 pm where a BPS member will coordinate dinner at a local restaurant. e-Poster Gallery The e-Poster Gallery offers presenters the opportunity to share their work online using high-quality graphics and allows conference attend- ees to browse through the virtual posters that are being presented. Attendees can log in to the mobile app or desktop planner to view the posters and optionally leave a comment, network with the presenter, or ask a question. Posters will be grouped by date/time/session as well as abstract category. The e-Poster Gallery will open February 14 for all registered attendees. Exhibits, Exhibit Hall ABC The Exhibit Hall features the most advanced equipment, products, ser- vices, and publications available. A list of exhibitors as of January 4, 2022 can be found beginning on page 169. Please see Addendum for those registered after January 10, 2022. Saturday 7:30 am –8:00 pm 7:30 am –6:30 pm 7:30 am –4:00 pm Sunday–Tuesday Wednesday

Sunday Monday Tuesday

10:00 am –5:00 pm 10:00 am –5:00 pm 10:00 am –4:00 pm

Exhibitor Lounge, Exhibit Hall C Exhibitors may visit the Exhibitor Lounge at the following times for assis- tance while at the meeting.

Friday

8:00 am –5:00 pm 8:00 am –3:00 pm 8:00 am –5:00 pm 8:00 am –5:00 pm 8:00 am –4:00 pm

Saturday Sunday Monday Tuesday

Wednesday

Closed

X

Mobile App and Desktop Planner The Biophysical Society’s Official Mobile App is available for download in the App Store and Google Play Store. iOS and Android Users can search for “Biophysical Society Events” to download the App. We do not support native apps for Windows Mobile, however, those users may access our mobile-friendly Desktop Planner at www.biophysics.org/2022meeting. Using the Mobile App you can view & create schedules, view abstracts/ authors/exhibitors, receive event alerts from BPS, Join the conversation in social media, find & interact virtually with other attendees, view the e-poster gallery, and sync itineraries that were created with the Desktop Planner. On-Demand Content On-Demand content will be accessible for all in-person attendees and on-demand registrants for viewing March 14, 2022, through April 30, 2022. Content includes: • 2022 Biophysical Society Lecturer, Frances Arnold, California Institute of Technology • 18 Subgroup Symposia • 4 Workshops • Society Awardee Talks One-on-One Mentor Session The Membership Committee is pleased to launch a new program called One-on-One with a Mentor. This program aims to connect Early Career and Student members with mentors at the Annual Meeting. We hope this connection will be helpful to you during your time at the meeting. Each mentor will only be assigned one mentee, on a first-come, first- served basis. BPS will try our best to match mentor-mentee pairs based on your answers to the questionnaire, your areas of research, Subgroup membership, etc. Parking There are many parking options — both garages and lots — conveniently located within blocks of the Moscone Center. Additionally, San Francisco has several thousand metered and non-metered timed spaces around the Moscone Center. Meter rates vary per hour depending upon wheth- er the meter is in a central location. Meter debit cards are available for purchase through the city of San Francisco. Please pay attention to the posted meter and regulation signs, including scheduled street cleaning and commuter lane restrictions. Poster Pickup Posters ordered in advance through Tray Printing will be available for pick up at the Moscone Center South, Exhibition Level, outside the Exhibit Hall entrance during the following hours: Saturday 4:00 pm –7:00 pm Sunday–Tuesday 9:00 am –11:00 am and 1:00 pm –4:00 pm No Wednesday Pick up Poster Sessions, Exhibit Hall ABC Sunday–Wednesday The Exhibit Hall will open at 8:00 am each morning. It will remain open for poster viewing until 10:00 pm each night, except for Tuesday, when it will close at 4:00 pm for safety purposes during exhibit tear down. Posters are arranged according to topic. Your poster board number begins with “B.” On the day of presentation, authors assigned odd-numbered poster boards should present 1:45 pm –2:45 pm (10:30 am –11:30 am on Wednesday); even-numbered posters should present 2:45 pm –3:45 pm ,

Exhibitor Passport Competition Pick up a Passport Competition booklet inside the entrance of the Exhibit Hall. Visit participating exhibitors, get your passport stamped, and drop your passport at the Society Booth located in the South Lobby before 2:30 pm Tuesday. The winner will be announced on Tuesday at 3:00 pm in the Exhibit Hall. You must be present at the drawing to win. Good luck! Family Room, South Lobby, Room 101 The Family Room is equipped with diapers, electrical outlets for pumps, labels for breast milk, plastic bags for disposing of diapers, a small refrigerator, private areas for nursing, and a small area for rest and play.

Friday

2:00 pm –5:00 pm 8:00 am –7:00 pm 7:30 am –10:00 pm 8:00 am –3:30 pm

Saturday

Sunday–Tuesday

Wednesday

First Aid, South First Aid In case of medical emergency, dial 511 from any house phone or 415- 978-3511 from a cell phone. For other minor medical needs, this room will be staffed with First Aid Administrators trained in First Aid Response during the hours below.

Saturday Sunday Monday Tuesday

7:30 am –6:30 pm 7:30 am –6:30 pm 7:30 am –9:30 pm 7:30 am –6:30 pm 7:30 am –3:30 pm

Wednesday

Image Contest Vote for your favorite image in the Image Contest! To showcase the artistic side of scientific imaging, a panel of judges has selected 10 final- ists to display their image at the Annual Meeting. These 10 images will be on display in the Exhibit Hall during the following hours: Sunday – Monday 10:00 am –5:00 pm Tuesday 10:00 am –2:30 pm Attendees will have the opportunity to vote for their two favorite images during these times. First, second, and third place winners will be announced on Tuesday afternoon at 3:00 pm in the Exhibit Hall. The 2022 Art of Science Image Contest is fully supported by Chroma Technology. Individuals Requiring Assistance Attendees requiring special assistance during the meeting should visit the Society Meeting Office in the South Lobby, Room 105, of the Moscone Center. Society staff will do their best to accommodate requests, however, we cannot ensure that special needs will be met Wireless Internet access is available free-of-charge throughout the common areas of the Moscone Center, excluding the Exhibit Hall. Meditation Room, South Lobby, Room 102 A room will be available for attendees to use for quiet meditation or prayer. Saturday–Tuesday 8:00 am –10:00 pm Wednesday 8:00 am –3:30 pm without prior notice. Internet Access

XI

Social Media Society staff will be updating the BPS Facebook page, Twitter feed, Instagram account, and blog with Annual Meeting information through- out the meeting. Follow us on: Twitter: @BiophysicalSoc, use hashtag #bps22 Facebook: www.facebook.com/biophysicalsociety Instagram: @biophysicalsociety Blog: www.biophysics.org/blog Social Media/Photography Policy The Biophysical Society welcomes the use of social media to share information from the 66th Biophysical Society Annual Meeting and to engage with the biophysics community. Please use the Annual Meeting hashtag #bps2022 when posting to help others follow along. We encourage you to share highlights from the meeting, suggest sessions to attend, discuss stand-out presentations and posters, and connect with your fellow biophysicists, as well as our sponsors and exhibitors. When sharing information about what you see and hear in meeting sessions, please refrain from photographing or sharing full detail of the material presented in order to respect the intellectual property of the presenters. Some presenters may request, verbally or in writing, that attendees not share information about their presentations and content; please honor those requests so that we can maintain a profes- sional, respectful environment. Presenters: If you do not wish to have your research shared via social media, please make an announcement before and during your pre- sentation. BPS strongly encourages compliance with speaker requests regarding social media sharing but cannot guarantee it. Due to the sensitive nature of data and the preliminary, unpublished research findings, all filming and recording of any kind (camera, cell phones, personal devices) in the scientific session rooms, Exhibit Hall, and poster area is strictly prohibited unless accompanied by a mem- ber of the Society staff. Any individual seen taking photographs in any session room, the Exhibit Hall, or poster area will be escorted out by security. Society Meeting Office, Room 105 Friday 3:00 pm –5:00 pm Saturday 7:30 am –6:30 pm Sunday–Tuesday 7:30 am –5:00 pm Wednesday 8:00 am –3:00 pm Speaker Ready Room, Room 104 We highly encourage all presenters in symposia, workshops, and plat- form sessions to visit the Speaker Ready Room one day prior to their scheduled presentation time. This room will be set up for your use and will contain several screens and data projectors to allow you the oppor- tunity to review your material prior to your scheduled presentation time slot. All speakers must bring their own laptops. An audiovisual technician will be available during room hours to assist you in setting up your laptop with the data projector and to answer any questions. As a courtesy to other presenters, please limit your viewing time to five minutes during peak times. Saturday–Tuesday 8:00 am –6:30 pm Wednesday 8:00 am –1:00 pm Data projectors will be provided in all session rooms in the Moscone Center. The data projectors will be compatible with both Windows and Mac laptops. Speakers must bring their own laptops. The Society does not provide laptops for those with flash drives or other storage devices.

(11:30 am –12:30 pm on Wednesday). Other hours, day or evening, may be posted by the authors as desired. Additionally, authors may leave note paper so that visitors may request an appointment. Abstracts submitted after October 1, 2021, are scheduled each day, Sunday–Wednesday, during the regular poster sessions. These board assignments will begin with “LB.” Posters are to be removed by 5:30 pm on Sunday and Monday, 4:00 pm on Tuesday in order to accommodate exhibits tear down, and 3:00 pm on Wednesday. Please do not leave materials or belongings under poster boards or in the poster area. The Society is not responsible for any articles left in the poster area. Proof of Vaccination and International Travel The City of San Francisco is requiring proof of vaccination, and if eligible, a booster is mandatory to enter the Moscone Center. This includes presenters, attendees, exhibitors, vendors, guests, and staff. Vaccines authorized by the US FDA or by the World Health Organization (WHO) will satisfy the City of San Francisco requirements. Vaccinations must be verified through CrowdPass, a HIPPA compliant service provider. Proof of negative COVID test and/or exemptions are not accepted. All international travelers will need to get a COVID-19 viral test (regard- less of vaccination status or citizenship) no more than 1 day before you travel by air into the United States. You must show your negative result to the airline before you board your flight. Raffles Exhibitor Raffle: Want to win a Samsung Galaxy Tablet? Pick up an Exhibitor Passport Competition booklet inside the entrance of the Exhibit Hall. Visit participating exhibitors, talk to them to find out the answer to their question, get your passport stamped, and drop off your passport at the Society Booth located in the South Lobby before 2:30 pm on Tuesday, February 22. The winner will be announced on Tuesday at 3:00 pm in the Exhibit Hall. You must be present at the drawing to win. Good luck! Wednesday Poster Session Raffle: Attend the Wednesday poster ses- sions in the Exhibit Hall for a chance to win a Fitbit Versa! Drop your ticket in the ballot box in the Exhibit Hall. The winner will be announced at 12:30 pm on Wednesday in the Exhibit Hall. You must be present in the Exhibit Hall to win. Good luck! Stop by the Society Booth to answer the biophysics trivia question for a chance to win a t-shirt each day Saturday–Tuesday. Restrooms Restrooms are located in the Exhibit Hall, Lobby Level, Upper Mezzanine, Level Two, and Level Three. Gender inclusive restrooms are located in the back of Exhibit Hall B, back of South Lobby, Esplanade Ballroom Level, Level 2 outside of Room 213, and Level 3 outside of Room 301. Sirens The City’s Outdoor Warning System is designed to alert residents and visitors of San Francisco about possible danger. Specific emergency announcements can be broadcast over any one of the 65 sirens that are located on poles and on top of buildings throughout all neighborhoods in San Francisco, Treasure Island, and Yerba Buena. They are tested at noon every Tuesday. During the weekly test, the siren emits a single 15-second alert tone, similar to an emergency vehicle siren. In the event of a disas- ter, the 15-second alert tone will sound repeatedly for 5 minutes. If you hear the siren at a time other than during its regular test on Tuesday at Noon: • Stop what you are doing • Stay calm • Listen for possible voice announcements • Turn on the radio or television (such as KCBS 740AM, KQED 88.5 FM) for important information provided by the city. • Avoid using the telephone. Do not call 911 unless you have a life threatening emergency.

XII

Transportation

Taxis Taxis will be available from the South Lobby of the Moscone Center. SF Green Cab. ................415-626-4733 Yellow Cab. ....................415-333-3333 National Cab Co.............415-648-4444 Undergraduate Student Lounge, Room 103 This special space is reserved for undergraduate meeting attendees looking for a place to relax or catch up on coursework they may be

BART and Muni Railways The Moscone Center is located a few blocks from both the BART and Muni Railways. To get to the Moscone Center, you will dis- embark at the Powell Street Station and exit to 4th and Market Streets. Turn right on 4th. Walk two blocks south to Howard and turn left. Taking BART from San Francisco International Airport Station can bring you directly to the Powell Station and should take approximately 20 minutes. CalTrain From the CalTrain Station (Fourth and Townsend). Across 4th Street from the train station, catch either the #30 or #45 lines. Get off at Third and Folsom. Walk one block north toward Howard Street. Turn left on Howard.

missing while at the Annual Meeting. Saturday–Tuesday 8:00 am –6:00 pm Wednesday

8:00 am –12:00 noon

Governance and Committee Meetings All rooms are located in the Moscone Center , unless otherwise noted.

3:30 pm –5:00 pm Early Careers Committee Meeting South, Level Three, Room 312 4:00 pm –6:00 pm Biophysical Journal Associate Editors Meeting South, Level Three, Room 311 7:00 pm –10:30 pm BPS Editors Dinner InterContinental Hotel, 4th Floor, Pacific Terrace Monday, February 21 8:30 am –10:30 am

Friday, February 18 3:30 pm –4:30 pm

Tuesday, February 22 8:00 am –9:00 am Biophysical Society Business Meeting Esplanade, Room 156 9:00 am –10:30 am Subgroup Chairs Meeting South, Level Three, Room 313/314 3:00 pm –5:00 pm Education Committee Meeting South, Level Three, Room 311 6:00 pm –10:00 pm Publications Committee Meeting Marriott Marquis, SOMA Wednesday, February 23 8:00 am –11:00 am New Council Meeting South, Level Three, Room 313/314

New Council Orientation Marriott Marquis, Pacific A 5:00 pm –9:00 pm Joint Council Reception, Dinner, and Meeting Marriott Marquis, SOMA Saturday, February 19 8:30 am –11:30 am Joint Council Meeting (continued) Marriott Marquis , SOMA Sunday, February 20 8:30 am –10:30 am Committee for Inclusion and Diversity Meeting South, Level Three, Room 312 12:00 pm –1:30 pm Public Affairs Committee Meeting South, Level Three, Room 312

CPOW Committee Meeting South, Level Three, Room 312 3:30 pm –5:30 pm Membership Committee Meeting South, Level Three, Room 312

The Biophysical Society would like to thank Society members who serve on Council or Committees for their dedication and efforts.

XIII

Professional Development & Educational Sessions

The Society’s committees have planned a variety of professional development activities to take place during the Annual Meeting. Below is a schedule of all of those activities. Detailed descriptions of the sessions can be found in the daily program. In addition, a student lounge for undergraduates will be available Sunday, February 20, to Wednesday, February 23, in South Lobby, Room 103. Sessions in italics will be held in Career Development Center, Esplanade 151.

Monday, February 21, 2022 7:30 am –8:30 am

Graduate Student Breakfast

9:00 am –10:00 am

Demystifying the Academic Job Search II: Preparing your Written Application Materials Networking for Biophysicists: How to Create Your Unicorn Career Annual Meeting of the Student Chapters Translating Your Credentials: Writing Effective Resumes + Cover Letters for Industry, Government, and Nonprofit Jobs Beyond Coronavirus: Preparing for the Next Pandemic Biophysics 101: Liquid-Liquid Phase Separation: Biophysical Fundamentals to Cellular Function The Future of Publishing and Why You Should Care Optimize Every Experience: How to Extract Value and Leverage Your Postdoc, Grad Experience and Internship to Advance in Your Career (#SpoilerAlert: There’s Much More Than You Think!) Rebuilding Research-Group Momentum During the COVID-19 Era Marketing Your Value: Crafting Your Elevator Pitch/30 Second Value Statement/Brand Statement The World Outside the Lab

10:30 am –11:30 am

11:00 am –1:00 pm 12:00 pm –1:00 pm

Saturday, February 19, 2022

1:00 pm –2:30 pm

3:00 pm –4:00 pm

Leveraging LinkedIn in the PhD Job Search: Networking, Informational Interviews, and More Undergraduate Poster Award Competition

1:30 pm –3:00 pm

3:00 pm –5:00 pm

1:30 pm –3:30 pm 2:15 pm –3:45 pm

One-on-One Resume and Career Counseling* 2:00 pm –2:40 pm | 4:30 pm –4:50 pm

2:30 pm –3:30 pm

Sunday, February 20, 2022 7:30 am –8:30 am

Postdoctoral Breakfast

2:30 pm –4:00 pm

9:00 am –10:00 am

Networking for Biophysicists: How to Create Your Unicorn Career Undergraduate Student Pizza “Breakfast” Demystifying the Academic Job Search I: Understanding the Search Process from the Perspective of Search Committees and Decoding Job Announcements Education and Career Opportunities Fair Teaching Science Like We Do Science Focus on Teaching: Building Your Career as a Teacher People or Projects? Approaches to Funding Research Nailing the Job Talk, or Erudition Ain’t Enough

4:00 pm –5:00 pm

11:30 am –1:00 pm 12:00 pm –1:00 pm

4:30 pm –6:00 pm Speed Networking One-on-One Resume and Career Counseling* 9:00 am –1:10 pm | 2:30 pm –4:30 pm | 5:20 pm –6:00 pm

1:00 pm –3:00 pm 2:00 pm –4:00 pm 2:30 pm –3:30 pm

Tuesday, February 22, 2022

2:30 pm –4:00 pm

9:30 am –10:30 am

Looking Beyond Academia: Identifying Your Career Options using MyIDP, LinkedIn and More Transitioning Your Career Beyond Academia Founding, Establishing, and Maintaining a Research Laboratory at Primarily Undergraduate Institutions

4:00 pm –5:00 pm 4:00 pm –6:00 pm

11:30 am –12:30 pm 12:00 pm –1:30 pm

PI to PI, a Wine and Cheese Mixer

One-on-One Resume and Career Counseling* 9:20 am –1:00 pm | 2:30 pm –4:50 pm | 5:20 pm –5:40 pm

2:30 pm –3:30 pm

The Strategic Postdoc: How to Find and Leverage your Postdoc Experience

One-on-One Resume and Career Counseling* 9:00 am –12:00 pm | 2:00 pm –3:30 pm | 3:50 pm –5:00 pm

* Slots for the One-on-One Resume and Career Counseling sessions are available on a first-come, first-served basis and fill up quickly. You may sign up for a slot beginning at 12:00 noon on Saturday, February 19, in the Career Development Center, Esplanade, Room 152. Please come prepared with resumes, CVs, and other appropriate materials.

XIV

Career Development Center Information Esplanade, Room 151

Andrew Green earned his PhD at the University of California, Berkeley, and has over 17 years of experience working with graduate students, PhDs, and postdocs as a career advisor. Before returning to Berkeley, where he serves as Associate Director of the Career Center, he spent six years on the faculty of Connecticut College. His specialty is working with PhDs and postdocs in the sciences and engineering pursuing profes- sional opportunities in the business, government, and nonprofit sectors as well as those seeking faculty jobs. He has given invited presentations at major scientific meetings and research universities across the country; and appeared in the Chronicle of Higher Education , NatureJobs , and The Atlantic Online .

Alaina G. Levine is an award-winning entrepreneur, STEM career consul- tant, science journalist, professional speaker and corporate comedian. Her book, Networking for Nerds (Wiley, 2015), beat out Einstein (really!) for the honor of being named one of the Top 5 Books of 2015 by Physics Today. As President of Quantum Success Solutions, she is a prolific speaker and writer on career development and professional advance- ment for engineers and scientists. She has delivered over 700 speeches for clients in the US, EU, Mexico, Canada, Africa, and Asia, and has writ- ten over 400 articles in publications such as Nature, Science, Scientific American, National Geographic News Watch, and Smithsonian. She has served as a career columnist for Physics Today and is a regular contribu- tor to the American Physical Society’s APS News and ScienceCareers. She also writes “Your Unicorn Career”, a careers column for ScienceCareers about finding your professional bliss. Levine authored two online courses for Oxford University Press on career development and entrepreneur- ship, is a consultant, speaker, and writer for the Lindau Nobel Laureate Meetings, and served as the event manager for an international con- ference on phononics. She holds bachelor’s degrees in mathematics and anthropology with a certificate in Middle Eastern Studies from the University of Arizona, and studied at the American University in Cairo as a US Department of Defense Boren Fellow.

Job Postings Employers Stop by the Career Center to post your job opening today! All attendees will have access to your job posting while at themeeting and your job will be posted on our online Job Board as well. Search resumes for a perfect fit and schedule an interview while you’re onsite at the meeting. Job Applicants Looking for a job in biophysics? Stop by the Career Development Center and upload your resume for employers to view on the Job Board both onsite and online. You may also apply for posted jobs.

Find a Job. Post a Job. Visit the BPS Job Board today. https:/ biophysics-jobs.careerwebsite.com

XV